EPFL BioE Talks SERIES "Photoenzymatic Catalysis - Using Light to Reveal New Enzyme Functions"
Event details
| Date | 12.04.2021 |
| Hour | 16:00 › 16:30 |
| Speaker | Prof. Todd Hyster, Cornell University, Ithaca, NY (USA) |
| Location | Online |
| Category | Conferences - Seminars |
WEEKLY EPFL BIOE TALKS SERIES
(note that this talk is number one of a double-feature seminar - see details of the second talk here)
Abstract:
Enzymes are unparalleled in their ability to catalyze reactions with high levels of selectivity. This catalytic platform cannot be applied to all chemical transformations because nature uses a relatively conserved set of reaction mechanisms by comparison to the diverse reactivity discovered by synthetic chemists. In this talk, I will describe my group's effort to expand the catalytic functions available to oxidoreductases using various photo excitation strategies.
Bio:
Todd Hyster is a native of Apple Valley, Minnesota. He conducted his undergraduate studies at the University of Minnesota. He did his Ph.D. studies at Colorado State University, where he worked with Tomislav Rovis to develop cyclopentadiene ligands for Rhodium-catalyzed C–H activation processes. As part of his studies, he was a Marie Curie fellow in Thomas Ward's lab at the University of Basel where he developed an artificial metalloenzyme enzyme for asymmetric C–H activation reactions. After graduating in 2013, he joined Frances Arnold's lab at Caltech, where he was an NIH postdoctoral fellow evolving P450s to catalyze selective nitrene transfer reactions. In 2015 he started his independent career at Princeton University, developing the area of photoenzymatic catalysis. In January 2021, he moved to Cornell University, where he is currently an Associate Professor.
Zoom link (with registration) for attending remotely: https://go.epfl.ch/EPFLBioETalks
IMPORTANT NOTICE: due to restrictions resulting from the ongoing Covid-19 pandemic, this seminar can be followed via Zoom web-streaming only, (following prior one-time registration through the link above).
(note that this talk is number one of a double-feature seminar - see details of the second talk here)
Abstract:
Enzymes are unparalleled in their ability to catalyze reactions with high levels of selectivity. This catalytic platform cannot be applied to all chemical transformations because nature uses a relatively conserved set of reaction mechanisms by comparison to the diverse reactivity discovered by synthetic chemists. In this talk, I will describe my group's effort to expand the catalytic functions available to oxidoreductases using various photo excitation strategies.
Bio:
Todd Hyster is a native of Apple Valley, Minnesota. He conducted his undergraduate studies at the University of Minnesota. He did his Ph.D. studies at Colorado State University, where he worked with Tomislav Rovis to develop cyclopentadiene ligands for Rhodium-catalyzed C–H activation processes. As part of his studies, he was a Marie Curie fellow in Thomas Ward's lab at the University of Basel where he developed an artificial metalloenzyme enzyme for asymmetric C–H activation reactions. After graduating in 2013, he joined Frances Arnold's lab at Caltech, where he was an NIH postdoctoral fellow evolving P450s to catalyze selective nitrene transfer reactions. In 2015 he started his independent career at Princeton University, developing the area of photoenzymatic catalysis. In January 2021, he moved to Cornell University, where he is currently an Associate Professor.
Zoom link (with registration) for attending remotely: https://go.epfl.ch/EPFLBioETalks
IMPORTANT NOTICE: due to restrictions resulting from the ongoing Covid-19 pandemic, this seminar can be followed via Zoom web-streaming only, (following prior one-time registration through the link above).
Practical information
- Informed public
- Registration required
Organizer
- Prof. Ardemis Boghossian, EPFL
Contact
- Institute of Bioengineering (IBI), Dietrich REINHARD