EPFL BioE Talks SERIES "The Architecture of Organelle Contact Sites"
Event details
| Date | 06.11.2023 |
| Hour | 16:00 › 17:00 |
| Speaker | Prof. Wanda Kukulski, Institute of Biochemistry and Molecular Medicine, University of Bern (CH) |
| Location | Online |
| Category | Conferences - Seminars |
| Event Language | English |
WEEKLY EPFL BIOE TALKS SERIES
Abstract:
Organelles interact through close apposition of their membranes. Such contact sites serve the exchange of lipid molecules, calcium transport and organelle biogenesis. The mechanisms by which lipids are transferred across organelle contact sites are poorly understood because little is known about the underpinning supramolecular structure. We aim to reveal the architecture composed of proteins and apposing membranes and thereby shed light on how these microenvironments facilitate the transport of lipid molecules between organelles. Towards this goal, we employ correlative light and electron microscopy approaches including electron cryo-tomography. We complement these tools with live fluorescence imaging, biochemical and cell biological experiments.
Bio:
Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks
Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IF you are not attending in-person in the room, please make sure to
Abstract:
Organelles interact through close apposition of their membranes. Such contact sites serve the exchange of lipid molecules, calcium transport and organelle biogenesis. The mechanisms by which lipids are transferred across organelle contact sites are poorly understood because little is known about the underpinning supramolecular structure. We aim to reveal the architecture composed of proteins and apposing membranes and thereby shed light on how these microenvironments facilitate the transport of lipid molecules between organelles. Towards this goal, we employ correlative light and electron microscopy approaches including electron cryo-tomography. We complement these tools with live fluorescence imaging, biochemical and cell biological experiments.
Bio:
- Since 2020 Professor and group leader, Institute of Biochemistry and Molecular Medicine, University of Bern, Switzerland
- 2015 – 2020 Group leader, Division of Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, UK
- 2008 – 2014 Postdoc, European Molecular Biology Laboratory, Heidelberg, Germany
- 2007 – 2008 Postdoc, Biozentrum, University of Basel, Switzerland
- 2002 – 2006 PhD student, Biozentrum, University of Basel, Switzerland
- 1998 – 2002 Studies in Biology II, University of Basel, Switzerland
Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks
Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IF you are not attending in-person in the room, please make sure to
- send D. Reinhard a note before noon on seminar day, informing that you plan to attend the talk online, and
- be signed in on Zoom with a recognizable user name (not a pseudonym making it difficult or impossible to be identified).
Practical information
- Informed public
- Registration required
Organizer
- Prof. Giovanni D’Angelo, EPFL
Contact
- Institute of Bioengineering (IBI), Dietrich REINHARD