Harmonic Generation Microscopy as a Tool for Label-Free Structural and Functional Bioimaging
Event details
| Date | 28.05.2013 |
| Hour | 13:15 |
| Speaker |
Dr. Martin Vogel, Max Planck Institute of Biophysics Bio: since 2008 postdoctoral fellow at the institute 2006-2008 postdoctoral fellow at the Center for Nanoscale Systems and visiting scholar with the group of Professor X.S.Xie, Department of Chemistry and Chemical Biology, Harvard University, Cambridge MA, USA 2005-2006 project leader Steinbeis GmbH & Co. KG für Wirtschaftsförderung, Stuttgart, Germany 1999-2004 Ph.D. (physics) at the Medical Biophysics group (Prof. R.H.A. Fink), Institute of Physiology and Pathophysiology, University of Heidelberg 1993-1999 Master studies (physics) at the University of Heidelberg |
| Location |
CE103
|
| Category | Conferences - Seminars |
Second Harmonic Generation (SHG), Third Harmonic Generation (THG) and Coherent Anti-Stokes Raman Scattering (CARS) Microscopy are versatile imaging modalities that find use in a broad range of applications, including material research and the life sciences. Readily available on almost any two photon microscope system, they probe sample features that are complementary to standard imaging modalities, and contrast is often generated without any extrinsic staining. I will discuss the basic characteristics of harmonic generation microscopy and present original data from various biological samples, including muscle, skin and peripheral nerve tissue. Finally, I will present an approach to study the conformational change of motor proteins in muscle using intrinsic SHG signals only.
Practical information
- General public
- Free