Human Organs on Chips and Programmable Nanotherapeutics at the Wyss Institute

Event details
Date | 19.09.2012 |
Hour | 11:15 |
Speaker | Donald E. Ingber, MD, PhD, Harvard University |
Location |
SV1717a
|
Category | Conferences - Seminars |
In this presentation, I will describe work we have been carrying out in the Programmable Nanomaterials and Biomimetic Microsystems platforms at the Wyss Institute for Biologically Inspired Engineering at Harvard, as well as our new model for innovation, collaboration and technology translation. The goal of the first platform is to create multi-functional nanotechnologies for regenerative medicine and drug delivery applications, with the long-term goal of developing injectable programmable devices for biomedicine. The second seeks to engineer microchips lined by living human cells that recapitulate organ-level functions as a way to replace animal testing for drug development. In this presentation, I will review recent advances we have made on development of human lung, gut and bone marrow chips and describe two new bioinspired nanotechnologies. The first is a Fluid Shear-Activated Drug Delivery System for injection of therapeutics that one desires to target to embolic or stenotic vascular lesions. The second relates to a new methodology for producing programmable nanotherapeutic devices using DNA origami as a manufacturing system.
Practical information
- General public
- Free
Organizer
- Prof. J.A. Hubbell
Contact
- Reinhard Dietrich <[email protected]>