Injectable Biomaterials for Treating Cardiovascular Disease
Event details
| Date | 19.10.2015 |
| Hour | 13:30 |
| Speaker | Prof. Karen L. Christman, University of California, San Diego, CA (USA) |
| Location | |
| Category | Conferences - Seminars |
BIOENGINEERING SEMINAR
Abstract:
Cardiovascular disease remains the leading cause of death in the western world. Two major types of cardiovascular disease, myocardial infarction and peripheral artery disease, have few available treatments and therefore numerous patients continue to decline towards heart failure for the former and amputation for the latter. Current clinical trials have focused on cell therapies; however it is largely acknowledged that these cells act via paracrine mechanisms to recruit endogenous cells to help repair and regenerate the tissue. In animal models, it has been established that cellular recruitment to the damaged tissue can also occur via implantation of biomaterial scaffolds. Injectable materials are particularly attractive since they have the potential to be delivered minimally invasively, thereby requiring less recovery time and reducing the chances of infection. This talk will cover recent developments and translational progress with the use of injectable biomaterials for treating cardiovascular disease.
Bio:
2000 B.S. in Biomedical Engineering, Northwestern University
2003 Ph.D. in Bioengineering, University of California San Francisco and Berkeley
2004-2007 Postdoc in Polymers and Nanotechnology, University of California Los Angeles
2007-2013 Assistant Professor, Department of Bioengineering, UCSD
2008 – Present Faculty Affiliate, Department of Nanoengineering, UCSD
2008 – Present Member, Materials Science Graduate Program, UCSD
2009 – Present Member, Institute of Engineering and Medicine, UCSD
2011 – Present Member, Clinical & Translational Research Institute, UCSD
2013 – Present Associate Professor, Department of Bioengineering, UCSD
Abstract:
Cardiovascular disease remains the leading cause of death in the western world. Two major types of cardiovascular disease, myocardial infarction and peripheral artery disease, have few available treatments and therefore numerous patients continue to decline towards heart failure for the former and amputation for the latter. Current clinical trials have focused on cell therapies; however it is largely acknowledged that these cells act via paracrine mechanisms to recruit endogenous cells to help repair and regenerate the tissue. In animal models, it has been established that cellular recruitment to the damaged tissue can also occur via implantation of biomaterial scaffolds. Injectable materials are particularly attractive since they have the potential to be delivered minimally invasively, thereby requiring less recovery time and reducing the chances of infection. This talk will cover recent developments and translational progress with the use of injectable biomaterials for treating cardiovascular disease.
Bio:
2000 B.S. in Biomedical Engineering, Northwestern University
2003 Ph.D. in Bioengineering, University of California San Francisco and Berkeley
2004-2007 Postdoc in Polymers and Nanotechnology, University of California Los Angeles
2007-2013 Assistant Professor, Department of Bioengineering, UCSD
2008 – Present Faculty Affiliate, Department of Nanoengineering, UCSD
2008 – Present Member, Materials Science Graduate Program, UCSD
2009 – Present Member, Institute of Engineering and Medicine, UCSD
2011 – Present Member, Clinical & Translational Research Institute, UCSD
2013 – Present Associate Professor, Department of Bioengineering, UCSD
Practical information
- Informed public
- Free