Conferences - Seminars

  Monday 19 June 2017 12:15 SV1717

Integrated Single-cell Analysis for Discovery and Development

By Prof. J. Christoper Love, Massachusetts Institute of Technology, Cambridge, MA (USA)

(sandwiches served)

The advance of technologies that use nanoliter-scale volumes in microfabricated systems to isolate individual cells is enabling new capabilities for measuring multiple attributes of each, including genomic, phenotypic and functional characteristics.  These technologies also provide an opportunity to examine intercellular interactions among discrete numbers of cells, allowing measurements of cooperativity and time-dependent activities.  This talk will describe a technology platform based on arrays of subnanoliter wells, and associated methods, that allow integrated measurements of cellular traits.  Applications of this platform to examine cellular phenotypes and interactions of immune cells will be discussed.  The capabilities provide new approaches to the discovery of rare cells and novel biomarkers in disease.

J. Christopher Love is an Associate Professor of Chemical Engineering at the Koch Institute for Integrative Cancer Research at MIT.  He is also an Associate Member of the Broad Institute, and an Associate Member at the Ragon Institute of MGH, MIT, and Harvard. Love earned a B.S. in chemistry from the University of Virginia and a Ph.D. in physical chemistry at Harvard University under the supervision of George Whitesides. Following completion of his doctoral studies, he extended his research into immunology at Harvard Medical School with Hidde Ploegh from 2004-2005, and at the Immune Disease Institute from 2005-2007. Dr. Love was a W.M. Keck Distinguished Young Scholar for Medical Research and a Dana Scholar for Human Immunology in 2009, a Life Sciences Research Foundation Postdoc Fellow (Gilead Sciences) in 2004, and a National Defense Science and Engineering Graduate Fellow from 1999-2002. He was also awarded the Foresight Distinguished Student Award in Nanotechnology in 2000. Love is also a Camille Dreyfus Teacher-Scholar.

Organization Prof. Hatice Altug

Contact Institute of Bioengineering (IBI, Christina Mattsson)

Accessibility Informed public

Admittance Free