Mechanosensing via the T Cell Receptor

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Event details

Date 06.05.2019
Hour 12:15
Speaker Prof. Cheng Zhu, Georgia Institute of Technology, Atlanta, GA (USA)
Location
Category Conferences - Seminars
WEEKLY BIOENGINEERING COLLOQUIA SERIES
(sandwiches served)

Abstract:
The immune response is orchestrated by a variety of immune cells, the function of which then is determined by the collective signals from different immunoreceptors. Mechanoimmunology is the study of how immune cells sense, respond, adapt, function, and develop in their stressful and changing mechanical environment. In this talk, I will present data showing the important role of physical forces in regulating antigen recognition/discrimination and function.  In particular, I will share with the audience our current understanding of the mechanosensing properties and mechanism of the T cell receptor, as well as the consequences in downstream signal transduction and function.

Bio:
Dr. Zhu began his research career as a theoretician building mathematical models of cellular processes. After coming to Georgia Tech, Dr. Zhu established his laboratory and is currently conducting research in the full spectrum of integrated experimental, computational, and theoretical studies in bioengineering at the cellular and molecular levels. Dr. Zhu began at Tech in 1990 as an Assistant Professor. Prior, he was an Assistant Research Bioengineer at the University of California at San Diego.

Education:
  • Ph.D., Columbia University, 1988
  • M.S., Columbia University, 1985
  • B.S., Zhejiang University, China, 1982

Zoom link for attending remotely:  https://epfl.zoom.us/j/950944776
 

Practical information

  • Informed public
  • Free

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