Mechanosensing via the T Cell Receptor

Event details
Date | 06.05.2019 |
Hour | 12:15 |
Speaker | Prof. Cheng Zhu, Georgia Institute of Technology, Atlanta, GA (USA) |
Location | |
Category | Conferences - Seminars |
WEEKLY BIOENGINEERING COLLOQUIA SERIES
(sandwiches served)
Abstract:
The immune response is orchestrated by a variety of immune cells, the function of which then is determined by the collective signals from different immunoreceptors. Mechanoimmunology is the study of how immune cells sense, respond, adapt, function, and develop in their stressful and changing mechanical environment. In this talk, I will present data showing the important role of physical forces in regulating antigen recognition/discrimination and function. In particular, I will share with the audience our current understanding of the mechanosensing properties and mechanism of the T cell receptor, as well as the consequences in downstream signal transduction and function.
Bio:
Dr. Zhu began his research career as a theoretician building mathematical models of cellular processes. After coming to Georgia Tech, Dr. Zhu established his laboratory and is currently conducting research in the full spectrum of integrated experimental, computational, and theoretical studies in bioengineering at the cellular and molecular levels. Dr. Zhu began at Tech in 1990 as an Assistant Professor. Prior, he was an Assistant Research Bioengineer at the University of California at San Diego.
Education:
Zoom link for attending remotely: https://epfl.zoom.us/j/950944776
(sandwiches served)
Abstract:
The immune response is orchestrated by a variety of immune cells, the function of which then is determined by the collective signals from different immunoreceptors. Mechanoimmunology is the study of how immune cells sense, respond, adapt, function, and develop in their stressful and changing mechanical environment. In this talk, I will present data showing the important role of physical forces in regulating antigen recognition/discrimination and function. In particular, I will share with the audience our current understanding of the mechanosensing properties and mechanism of the T cell receptor, as well as the consequences in downstream signal transduction and function.
Bio:
Dr. Zhu began his research career as a theoretician building mathematical models of cellular processes. After coming to Georgia Tech, Dr. Zhu established his laboratory and is currently conducting research in the full spectrum of integrated experimental, computational, and theoretical studies in bioengineering at the cellular and molecular levels. Dr. Zhu began at Tech in 1990 as an Assistant Professor. Prior, he was an Assistant Research Bioengineer at the University of California at San Diego.
Education:
- Ph.D., Columbia University, 1988
- M.S., Columbia University, 1985
- B.S., Zhejiang University, China, 1982
Zoom link for attending remotely: https://epfl.zoom.us/j/950944776
Practical information
- Informed public
- Free
Organizer
Contact
- Institute of Bioengineering (IBI), Christina Mattsson