Microfluidic Platforms for Controlling the in vitro Cellular Microenvironment

Event details
Date | 05.07.2013 |
Hour | 13:00 › 14:00 |
Speaker |
Francesco Piraino, Ph.D., Broad Institute, MIT and Harvard University, Cambridge, MA (USA) Bio: Francesco Piraino received his B.Sc. and M.Sc. degrees in Biomedical Engineering from Politecnico di Milano. During his master studies he spent a semester at the City University of New York, under Dr. Tarbell’s supervision. He started his doctoral studies in January 2009 and in December 2009 he was awarded a Progetto Roberto Rocca Fellowship to join the Brigham & Women’s Hospital and Harvard-MIT Division of Health, Science and Technology, supervised by Dr. Khademhosseini. He received his PhD in Biomedical and Biomechanical Engineering in March 2012 from the Interpolytechnic School of Doctorate. He is now a Post-doctoral Associate at the Broad Institute of MIT and Harvard. His current research focuses on the development of droplet microfluidic devices for single-cell high-throughput screening. |
Location | |
Category | Conferences - Seminars |
The cellular microenvironment provides cells with physical architecture, soluble and adhesive signals, growth factors, nutrients, inhibitor chemicals, and cell-cell interactions. The in vivo cellular microenvironment is composed of an intricate mixture of extracellular matrix proteins, proteoglycans, small molecule signals and various adjacent cell types. These vary in space and time due to material deformation, fluid flow, chemical reactions; or cell proliferation, differentiation, death, and migration. Cells continually sense these inputs, process the information and execute a behavior. Therefore, to study cells under well-controlled conditions in vitro or to manipulate cells for clinical applications, it is important to recreate the physiological microenvironment.
In this seminar, microfluidic platforms for applications including drug and material screening, and high-throughput cell analysis will be discussed.
In this seminar, microfluidic platforms for applications including drug and material screening, and high-throughput cell analysis will be discussed.
Links
Practical information
- Informed public
- Free
- This event is internal
Organizer
- Prof. Sebastian Maerkl