microRNA Control of the Innate Immune Response

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Date 10.06.2013
Hour 14:3015:30
Speaker Prof. Brian D. Brown, Mt Sinai School of Medicine, New York
Bio: Situated in the Mount Sinai School of Medicine in New York, our laboratory is studying fundamental aspects of microRNA biology and developing new approaches that exploit endogenous microRNA regulation to modulate the host immune system.  We hope that through this research we will be able to improve therapies aimed at treating autoimmune diseases, such as type I diabetes, and better target cancers.
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Category Conferences - Seminars
My lab is studying some of the fundamental questions in microRNA biology, including how microRNA concentration relates to target suppression.  We have developed a novel technology that enables high-throughput analysis of microRNA activity, which has provided us with relevant new insight into this question. We are also investigating the role of microRNAs in the host response to pathogens.  We have recently discovered a microRNA with a previously unappreciated function in controlling the innate response to pathogen-associated nucleic acids.  We are currently working to decipher the specific role and regulatory targets of this miRNA.

Practical information

  • Informed public
  • Free
  • This event is internal

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Tags

Immunology Immunological Tolerance Infectious Disease Inflammation Antigen Presentation Dendritic Cells Autoimmunity Diabetes Molecular Biology Gene Discovery Gene Expressions Gene Regulation RNA RNA Regulation microRNA Regulation of the Innate Immune System

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