Organic Chemistry Seminar by Prof. Jakub Svenda - CH-635
Event details
| Date | 30.11.2022 |
| Hour | 16:15 › 17:15 |
| Speaker | Prof. Jakub Svenda Masaryk University, Czech Republic |
| Location | |
| Category | Conferences - Seminars |
| Event Language | English |
Title: Reducing synthetic complexity of the bactobolin class of ribosome inhibitors
Abstract:
Natural products remain an important source of bioactive molecules for basic research and drug discovery. Changes to the structure and consequently properties of many natural products, notwithstanding their potential, remain non-trivial by the currently available technologies, including chemical synthesis. In this lecture, I will describe how strategic planning and ever-evolving synthetic methods helped us overcome the synthetic complexity of bactobolins, an underexplored class of naturally occurring ribosome inhibitors. Simple access to synthetic bactobolins enables broad investigation of this natural product family.
Speaker's biography:
Ph.D., Harvard University (Andrew G. Myers), 2004-2010
Humboldt Postdoctoral Fellow, Max Planck Institute (Herbert Waldmann), 2010-2012
Assistant Professor, Masaryk University, Czech Republic, 2013-present
Scientist, International Clinical Research Center, Czech Republic, 2013-present
Lab website: https://orgsyn.sci.muni.cz/
Abstract:
Natural products remain an important source of bioactive molecules for basic research and drug discovery. Changes to the structure and consequently properties of many natural products, notwithstanding their potential, remain non-trivial by the currently available technologies, including chemical synthesis. In this lecture, I will describe how strategic planning and ever-evolving synthetic methods helped us overcome the synthetic complexity of bactobolins, an underexplored class of naturally occurring ribosome inhibitors. Simple access to synthetic bactobolins enables broad investigation of this natural product family.
Speaker's biography:
Ph.D., Harvard University (Andrew G. Myers), 2004-2010
Humboldt Postdoctoral Fellow, Max Planck Institute (Herbert Waldmann), 2010-2012
Assistant Professor, Masaryk University, Czech Republic, 2013-present
Scientist, International Clinical Research Center, Czech Republic, 2013-present
Lab website: https://orgsyn.sci.muni.cz/
Practical information
- Informed public
- Free