Parkinson's Pathway Molecular Data Analysis

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Event details

Date 28.09.2021  
Category Call for proposal
Event Language English
Aim:
The Outcome Measures Parkinson's Pathway Molecular Data Analysis Program aims to identify and characterize novel biomarkers and critical pathways from existing molecular data sets. This funding opportunity is intended for applications using existing and novel computational, informatic, and data science strategies to interrogate molecular data sets relevant to Parkinson's disease.

Applications should focus on studies that achieve one or more of the following goals:
  • Comparisons of analytes across complementary cohorts to identify or evaluate performance of putative biomarkers
  • Evaluation of underexplored genetic variants associated with PD risk and correlates with clinical or molecular features of disease.
  • Identification of novel molecular indicators of phenoconversion and/or PD subtyping.
  • Integrated analysis of multi-omic data sets to identify and characterize critical pathways disrupted in Parkinson’s disease
  • Identification of novel genotype-phenotype implications on molecular features of disease
  • Characterization of molecular indicators of the role of the immune system in PD risk and patient outcomes.
  • Identification or evaluation of molecular indicators of lysosomal and endosomal function, dysfunction, or functional diversity relevant to PD risk and penetrance
Amount: Applicants may request budgets ranging from $50,000 to $350,000 for projects meeting the application criteria. Requested budget amount will not correlate with prioritization for funding. Requested support should be commensurate with work proposed and must include clear explanation of costs.
Deadline:
  • Pre-proposals Due: September 28, 2021, 5 p.m. US ET
  • Full Proposals Due (by invite only): January 13, 2022, 5 p.m. US ET
Duration: 12 to 18 months
Eligibility: Applications may be submitted by researchers or clinicians in:
  • U.S. and non-U.S. biotechnology/pharmaceutical companies, or other publicly or privately held for-profit entities; and
  • U.S. and non-U.S. public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments and eligible agencies of the federal government.
  • Post-doctoral fellows are eligible to apply as co-investigators with the designation of an administrative primary investigator who directs the laboratory in which the fellow will conduct research. The administrative co-PI will be responsible for assisting in providing all institutional documents required for the project and will be required to sign any award contract. Training or mentoring-only proposals will not be considered.
How to Apply: For Further Information:

Practical information

  • General public
  • Free

Organizer

  • The Research Office

Tags

biomarkers of Parkinson's progression phenoconversion patient stratification

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