Physical Modeling and Computer Simulation of Sclerotic Arteries
Event details
| Date | 28.02.2012 |
| Hour | 13:15 |
| Speaker | Dr. Gerhard A. Holzapfel, Graz University of Technology, Austria and Royal Institute of Technology, Stockholm, Sweden |
| Location |
ME B3 31
|
| Category | Conferences - Seminars |
Sclerotic arteries can be considered as heterogeneous structures with materials undergoing large anisotropic deformations. The structural basis is the collagen which is the ubiquitous load-bearing and reinforcing element in the material. The organization of collagen fibers, and the tension within, maintains the function, integrity and strength of arteries. The presentation shows new experimental results on the collagen fiber orientations and dispersion in human arteries and suggests how to bring this information in a hyperelastic model. Thereby, the importance of considering structural data in a model is highlighted. It is also shown how the individual arterial components are assembled to a 3D geometrical model and discretized, which is then used for finite element analyses of angioplasty (a technique of mechanically widening a narrowed artery). The computer simulations consider balloon–stent–artery interaction and provide better insights into the related changes of the mechanical environment. For example, the stress distributions in the wall are strongly dependent on the stent design.
Practical information
- General public
- Free