PTEN Research - Improving understanding of disease mechanisms of PTEN Harmatoma Tumour Syndrome (PHTS)

Through this call, PTEN Research seeks to identify academic research proposals that aim to progress the understanding of the molecular and cellular mechanisms that are disrupted upon PTEN mutation/loss and that drive the pathobiology of PHTS. Within the broad spectrum of manifestations linked to PHTS, we are particularly interested in projects that are focused on the non-malignant aspects of PHTS, especially vascular anomalies and neurodevelopmental deficits, to align with the Foundation’s therapy development efforts.  The call is open to basic and translational research proposals, especially those that offer a translational pathway/potential future clinical impact.

Duration:   2-3 years

Funding:   GBP 220,000

Eligibility:
Eligibility to apply for funding is not restricted to any specific geography. Applications will only be considered from principal investigators who hold a MD or PhD and have an established research programme or faculty position in a recognised academic or clinical research institution.

How to Apply:
All submissions should be made by e-mail to [email protected]. PTEN Research will acknowledge submissions within a week of receipt. Applications submitted in response to this call will be evaluated in a two-step review process consisting of a Project Proposal stage, and a Full Application stage.

Application Deadline:      

• Project Proposal submission deadline: 28 June 2024
• Full Application submission deadline: 4 October 2024
• Applicants notified of outcome of application: by the end of February 2025

• More information about the program is available here