Simons Foundation | Linking Early Neurodevelopment to Neural Circuit Outcomes


Event details

Date 12.09.2024
Category Call for proposal

The Linking Early Neurodevelopment to Neural Circuit Outcomes RFA will support research that aims to directly connect neurodevelopmental changes to autism spectrum disorder (ASD)-relevant circuit phenotypes in order to advance our understanding of how ASD risk genes contribute to the neurobiology of autism. Simons invites proposals that will elucidate the impact of well-defined developmental alterations on the structure, function and/or output of neural circuits relevant to ASD phenotypes. To this end, experimental endpoints need not be behavioral readouts, but should be phenotypes that would reasonably be expected to drive alterations in function at the organism level (e.g., changes in synaptic connectivity or plasticity, or altered local or mesoscale neural dynamics and/or coding, ideally assessed with cell-type specificity).

Due to the multidisciplinary focus of this RFA, the foundation strongly encourages collaborative applications involving multiple principal investigators (PIs); single PI applications will also be accepted.


  • 3-4 years

  • Maximum $300,000/year/lab, inclusive of 20% indirect costs

Applications may be submitted by domestic and foreign nonprofit organizations; public and private institutions, such as colleges, universities, hospitals, laboratories and units of state and local government; and eligible agencies of the federal government. There are no citizenship or country requirements.

All applicants and key collaborators must hold a Ph.D., M.D. or equivalent degree and have a faculty position or the equivalent at a college, university, medical school or other research facility.

How to Apply:
Applications must be submitted via the Simons Award Manager (SAM). Please click on the Funding Opportunities icon and navigate to the Autism Research – “Development to Circuits” call. Click the Create Application button to begin. Applications should be started and submitted under the applicant’s own account in SAM.

Application Deadline:
  • 12 September 2024

Further information:
  • More information about the program is available here
  • Info session for potential applicants on 25 June, 12pm EDT
  • Application portal can be found here
  • For any other questions, please contact the Research Office.

Practical information

  • General public
  • Free


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