Smart fibers and textiles for medical applications

Thumbnail

Event details

Date 26.10.2015
Hour 13:1514:15
Speaker Dr. René Rossi, Swiss Federal Laboratories for Materials Science and Technology, St. Gallen
Location
Category Conferences - Seminars
Fibers, membranes and in general textiles are commonly worn around the body and are therefore ideal materials for the monitoring of vital body functions or for transdermal drug delivery systems. As they are flexible and robust; and present a unique surface-to-volume ratio, they can be used to develop wearable sensors with high wearing comfort and covering large body areas. For instance, optical fiber-based sensors have been used for the supervision of respiration, cardiac output, blood pressure, oxygen saturation, as well as the monitoring of pressure for the prevention of pressure ulcers [1]. Stimuli-responsive polymers that change their molecular structure in dependence of temperature, light or pH can be processed into fibers and membranes for different biomedical applications like highly-sensitive drug carriers with well-controlled delivery [2, 3]. In a recent project with the University hospital of Zurich, we developed a light-responsive membrane that will be used for the delivery of caffeine for preborn infants suffering from lung insufficiency [4]. The same membrane is intended to be used as part of a non-invasive glucose monitoring system. In this seminar, an overview of our research in the field of smart fibers and membranes for sensory and targeted delivery will be given.    


[1] Quandt, M., Scherer, L.J., Boesel, L., Wolf, M., Bona, G.L., Rossi, R.M., 2015, Body-monitoring and health supervision by means of optical fiber-based sensing systems in medical textiles, Adv. Healthcare Mat., 4 (3), 330-355

[2] Crespy, D., Rossi, R.M., 2007, Temperature-responsive polymers with LCST in the physiological range and their applications in textiles, Polymer Int., 56 (12), 1461-1468

[3] Ghitescu, R.E., Popa, A.M., Popa, V.I., Rossi, R.M., Fortunato, G., 2015 Polyphenols encapsulated in pHEMA e-spun fibers and determination of their antioxidant activities, Int. J. Pharmaceutics, 494, 278-287

[4] Schöller, K., Küpfer, S., Baumann, L., Hoyer, P.M., de Courten, D., Marti, D., Rossi, R.M., Vetushka, A., Wolf, M., Bruns, N., Scherer, L.J., 2014, From membrane to skin: aqueous permeation control through light-responsive amphiphilic polymer co-networks, Adv. Funct. Mat., 24, 5194-5201

Bio: Rene M. Rossi is physicist and obtained his PhD at ETH Zurich in the field of the complex man-clothing-environment interactions in a firefighting environment. Since 2003, he is the head of the Laboratory for Protection and Physiology at Empa, a group of 40 persons working in the field of high-tech fibres and textiles for near-to-body applications. One of the key topics of the laboratory are the development of textile-based sensors for medical applications.

Links

Practical information

  • General public
  • Free

Organizer

  • Fabien Sorin

Contact

  • Fabien Sorin

Event broadcasted in

Share