The Michael J. Fox Foundation | Seed Amplification Assay Innovation Program
Event details
| Date | 30.01.2025 |
| Category | Call for proposal |
Aim: This program seeks to advance the development of high-performance, quantitative alpha-synuclein seed amplification assays (aSyn-SAAs), addressing the critical need for less invasive, highly sensitive and quantitative biomarkers in Parkinson’s disease (PD) clinical trials
Research must address one or both critical gaps to integrate aSyn-SAA into clinical practice and therapeutic development:
Funding: Up to $1,000,000
Duration: 6-24 months
Eligibility: Applications may be submitted by researchers or clinicians in:
Deadline pre-proposal: 30 January 2025
Further information
Research must address one or both critical gaps to integrate aSyn-SAA into clinical practice and therapeutic development:
- Current aSyn-SAAs provide binary (positive/negative) results rather than quantitative assessment, precluding their use for monitoring disease progression and evaluating treatment effects.
- The invasiveness of spinal tap limits its utility in routine clinical practice, can delay or deter subject recruitment in clinical trials, has poor accessibility/acceptance in some geographies and is not amendable to request repeated sampling.
Funding: Up to $1,000,000
Duration: 6-24 months
Eligibility: Applications may be submitted by researchers or clinicians in:
- U.S. and non-U.S. biotechnology/pharmaceutical companies, or other publicly or privately held for-profit entities; and
- U.S. and non-U.S. public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments and eligible agencies of the federal government.
- Post-doctoral fellows are NOT eligible to apply as co-investigators.
Deadline pre-proposal: 30 January 2025
Further information
- More information about the program is available here and the full RFA is available here
- Application portal can be found here
- For any other questions, please contact the Research Office
Practical information
- General public
- Free