[ U.S. CDMRP - Breast Cancer Breakthrough Award Levels 1-4 | Research Funding ]
Event details
| Date | 12.03.2020 |
| Category | Call for proposal |
Aim: Through the Congressionally Directed Medical Research Program (CDMRP), the Department of Defense is announcing the Breast Cancer Breakthrough Awards. The intent of these Awards is to support promising research that has high potential to lead to or make breakthroughs in breast cancer. Scope: Research proposed under this award mechanism may be small- to large-scale projects, at different stages of idea and research development. Four different funding levels, based on the scope of the research, are available:
All FY20 BCRP Breakthrough Award Levels 1 and 2 applications must address at least one of the overarching challenges for FY20, which are listed at the end of this announcement.
Funding: max. $450’000 (Level 1)
max. $1’000’000 (Level 2)
max. $3’000’000 (Level 3)
max. $10’000’000 (Level 4)
Duration: 3 years
Eligibility: Applicants from international organizations or institutions are eligible to apply, and there are no citizenship restrictions. Investigators at all levels, including senior postdocs, are eligible to apply. A Mentorship Statement is required for applications submitted with a PI who is a postdoctoral fellow.
How to Apply: Pre-applications are submitted through the eBRAP platform. They should contain contact information, a letter of intent, and a list of collaborators and key personnel as suggested on the platform. Full applications (by invitation) will be made via a Grants.gov workspace. Full application packages can be downloaded from Grants.gov at any time.
Pre-Application Deadline, Levels 1-2: 12-Mar-2020, 5:00 p.m. EST
Pre-Application Deadline, Levels 3-4: 13-Mar-2020, 5:00 p.m. EST
Full Application Deadline, Levels 1-2: 26-Mar-2020, 11:59 p.m. EST
Full Application Deadline, Levels 3-4: 24-Jun-2020, 11:59 p.m. EST
Grants.gov Funding Opportunity Numbers:
W81XWH-20-BCRP-BTA12
W81XWH-20-BCRP-BTA3
W81XWH-20-BCRP-BTA4
Further information
FY20 Overarching Challenges
- Funding Level 1: Innovative, high-risk/high-reward research that is in the earliest stages of idea development. Research with potential to yield new avenues of investigation. Proof of concept. No preliminary data required.
- Funding Level 2: Preclinical research that is already supported by substantial preliminary or published data and strongly validates clinical translation in a well-defined context within the breast cancer landscape.
- Funding Level 3: Advanced translational studies with a high degree of project readiness. Where relevant, proof of availability of and access to necessary data, human samples, cohort(s) and/or critical reagents must be provided. Applications must state a realistic timeline for near-term clinical investigation. Small-scale clinical trials (e.g., first in human, Phase I/Ib) may be appropriate.
- Funding Level 4: Large-scale projects that will transform and revolutionize the clinical management and/or prevention of breast cancer. Human clinical trials are required.
All FY20 BCRP Breakthrough Award Levels 1 and 2 applications must address at least one of the overarching challenges for FY20, which are listed at the end of this announcement.
Funding: max. $450’000 (Level 1)
max. $1’000’000 (Level 2)
max. $3’000’000 (Level 3)
max. $10’000’000 (Level 4)
Duration: 3 years
Eligibility: Applicants from international organizations or institutions are eligible to apply, and there are no citizenship restrictions. Investigators at all levels, including senior postdocs, are eligible to apply. A Mentorship Statement is required for applications submitted with a PI who is a postdoctoral fellow.
How to Apply: Pre-applications are submitted through the eBRAP platform. They should contain contact information, a letter of intent, and a list of collaborators and key personnel as suggested on the platform. Full applications (by invitation) will be made via a Grants.gov workspace. Full application packages can be downloaded from Grants.gov at any time.
Pre-Application Deadline, Levels 1-2: 12-Mar-2020, 5:00 p.m. EST
Pre-Application Deadline, Levels 3-4: 13-Mar-2020, 5:00 p.m. EST
Full Application Deadline, Levels 1-2: 26-Mar-2020, 11:59 p.m. EST
Full Application Deadline, Levels 3-4: 24-Jun-2020, 11:59 p.m. EST
Grants.gov Funding Opportunity Numbers:
W81XWH-20-BCRP-BTA12
W81XWH-20-BCRP-BTA3
W81XWH-20-BCRP-BTA4
Further information
- To see the program announcement, navigate to the search page on Grants.gov and search for the Opportunity Numbers W81XWH-20-BCRP-BTA12, W81XWH-20-BCRP-BTA3, or W81XWH-20-BCRP-BTA4
- For questions about the eBRAP or Grants.gov platforms, contact the Research Office.
FY20 Overarching Challenges
- Prevent breast cancer (primary prevention)
- Identify determinants of breast cancer initiation, risk, or susceptibility
- Distinguish deadly from non-deadly breast cancers
- Conquer the problems of overdiagnosis and overtreatment
- Identify what drives breast cancer growth; determine how to stop it
- Identify why some breast cancers become metastatic
- Determine why/how breast cancer cells lie dormant for years and then re-emerge; determine how to prevent lethal recurrence
- Revolutionize treatment regimens by replacing them with ones that are more effective, less toxic, and impact survival
- Eliminate the mortality associated with metastatic breast cancer
Practical information
- General public
- Free