Conferences - Seminars

15JAN
2019
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  Tuesday 15 January 2019 16:15 SV 1717

Viscoelasticity of cell membranes: from minimal artificial cortices to living cells

By Prof. Andreas Janshoff

Andreas Janshoff is Full Professor for Biophysical Chemistry at the University of Göttingen, Germany and his major research interests include membrane biophysics, cell mechanics, sensor design and single-molecule force spectroscopy.

About the talk
A thin layer of actin filaments located underneath the plasma membrane in eukaryotic cells drives pivotal aspects of cell mechanics. Myosin-driven contractility and actin-cytoskeleton membrane interactions are responsible for fundamental cellular processes such as cytokinesis, cell migration, cortical flows, and also contributes to the response to external deformation. How the interplay between the actin cytoskeleton, the membrane, and actin binding proteins drives these processes is far from being understood. To unravel general principles underlying actin cortex properties, a bottom-up in vitro system has been developed and compared with apical cell membranes derived from living cells as well as living cells subject to various environmental cues.

About Andreas Janshoff
Andreas Janshoff, obtained a B.Sc. in Biology and a M.Sc. in Chemistry from the University of Muenster. Under the guidance of Hans- Joachim Galla, he received his PhD in 1997. After a postdoctoral stay at the Scripps Research Institute in La Jolla, CA (USA) in the group of Prof. M. Reza Ghadiri, he returned to the Institute of Physics at the University of Muenster in 1999 as a DFG-fellow. In 2001, Andreas Janshoff became associate professor inPhysical Chemistry at the Institute of Physical Chemistry at the Johannes Gutenberg University in Mainz and was appointed to a full professorship in Biophysical Chemistry in 2006. Since August 2008, he is a full professor in Biophysical Chemistry at the Institute of Physical Chemistry, Georg-August University of Göttingen (Germany). His main research focus is on soft matter physics and biophysical chemistry.

JanshoffEPFLWEB.pdf

Organization NCCR Chemical Biology

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