Biomedical MEMS Implants: Inorganic-Based, Polymer-Based, and Protein-Based Transducers
Event details
| Date | 06.12.2016 |
| Hour | 11:00 › 12:00 |
| Speaker | Prof. Dr. Mark G. Allen |
| Location | |
| Category | Conferences - Seminars |
EPFL IMT Distinguished Lecture Series
Abstract: Bioiplantable sensors based on microelectromechanical systems (MEMS) technology, that can communicate information from within the body to guide medical treatment of disease, will be presented. First, a permanently-implantable sensor for measurement of endovascular blood pressure will be discussed. These sensors, designed for chronic monitoring over the lifetime of the patient, detect the pressure within the pulmonary artery to allow titration of medication for patients with congestive heart failure. The second type of sensor is fabricated entirely of biodegradable materials. Such biodegradable implants may be appropriate for acute medical applications such as bone or wound healing as they potentially eliminate the need for implant extraction when sensing is no longer required. Biodegradable materials are particularly challenging to process using conventional MEMS fabrication techniques because they are water-sensitive. Alternative MEMS fabrication approaches were combined with traditional techniques to fabricate biodegradable sensors, interconnects, and power supplies. Finally, the use of protein materials as substrates for implantable MEMS will be discussed. Device experimental results, including clinical implementation of the permanent sensors (which are now commercially available) and bench results from the newer biodegradable and protein-based devices will be presented.
Bio: Mark Allen received degrees in chemistry, chemical engineering, and electrical engineering from the University of Pennsylvania (Penn) and MIT. In 1989 he joined Georgia Tech, ultimately becoming Regents’ Professor and the J.M. Pettit Professor in Microelectronics. In 2013 he returned to Penn to become Scientific Director of the Singh Center for Nanotechnology. He and his group have authored approximately 400 publications in various areas of MEMS, and he is co-founder of multiple MEMS companies, including CardioMEMS (which commercialized the first FDA-approved, wireless MEMS sensor for permanent endovascular implantation) and Axion Biosystems. He is a Fellow of the IEEE, and received the IEEE 2016 Daniel P. Noble Award for contributions to research and development, clinical translation, and commercialization of biomedical microsystems. More information can be found at: http://mems.seas.upenn.edu
Abstract: Bioiplantable sensors based on microelectromechanical systems (MEMS) technology, that can communicate information from within the body to guide medical treatment of disease, will be presented. First, a permanently-implantable sensor for measurement of endovascular blood pressure will be discussed. These sensors, designed for chronic monitoring over the lifetime of the patient, detect the pressure within the pulmonary artery to allow titration of medication for patients with congestive heart failure. The second type of sensor is fabricated entirely of biodegradable materials. Such biodegradable implants may be appropriate for acute medical applications such as bone or wound healing as they potentially eliminate the need for implant extraction when sensing is no longer required. Biodegradable materials are particularly challenging to process using conventional MEMS fabrication techniques because they are water-sensitive. Alternative MEMS fabrication approaches were combined with traditional techniques to fabricate biodegradable sensors, interconnects, and power supplies. Finally, the use of protein materials as substrates for implantable MEMS will be discussed. Device experimental results, including clinical implementation of the permanent sensors (which are now commercially available) and bench results from the newer biodegradable and protein-based devices will be presented.
Bio: Mark Allen received degrees in chemistry, chemical engineering, and electrical engineering from the University of Pennsylvania (Penn) and MIT. In 1989 he joined Georgia Tech, ultimately becoming Regents’ Professor and the J.M. Pettit Professor in Microelectronics. In 2013 he returned to Penn to become Scientific Director of the Singh Center for Nanotechnology. He and his group have authored approximately 400 publications in various areas of MEMS, and he is co-founder of multiple MEMS companies, including CardioMEMS (which commercialized the first FDA-approved, wireless MEMS sensor for permanent endovascular implantation) and Axion Biosystems. He is a Fellow of the IEEE, and received the IEEE 2016 Daniel P. Noble Award for contributions to research and development, clinical translation, and commercialization of biomedical microsystems. More information can be found at: http://mems.seas.upenn.edu
Practical information
- Informed public
- Free