BMI SEMINAR // Hypothalamic circuits for cognition and action
Event details
| Date | 05.12.2018 |
| Hour | 12:15 › 13:15 |
| Speaker | Denis Burdakov, Dept. Of Health Sciences and Technology, ETH Zürich, CH |
| Location | |
| Category | Conferences - Seminars |
Lesions of the hypothalamus severely impair motor and cognitive functions, indicating a critical role for hypothalamus in these processes.
However, underlying circuits and neural dynamics are poorly understood. The hypothalamus contains several genetically-distinct classes of brain-wide projecting neurons, such are orexin and melanin-concentrating-hormone neurons, which co-release these neuropeptides with GABA or glutamate. We have been probing how these neurons orchestrate the rest of the brain to control specific cognitive and behavioural acts, by combining cell-type-specific in vivo recordings with functional circuit mapping, and optogenetic and chemogenetic control of defined neurons during quantified freely-moving behaviour. We defined several genetically-distinct hypothalamic circuits whose natural dynamics exert powerful influence on action selection and memory.
Practical information
- Informed public
- Free
Organizer
- SV BMI Host : C. Petersen
Contact
- brain_mind@epfl.ch