Conferences - Seminars
BMI SEMINAR // Impulse control: from the urge to its inhibition, a transnological approach to the vulnerability to compulsive disorders
By David Belin, Behavioural and Clinical Neuroscience Institute, Department of Psychology, University of Cambridge, UK
It has long been suggested that failure appropriately to inhibit impulses stems from a deficit in prefrontal cortical inhibitory function. Here it will be suggested that impulsivity, which predicts the vulnerability to develop addiction to stimulant drugs as well as compulsive behaviours as observed in Obsessive Compulsive Disorder and early onset Parkinson’s Disease, also stems from an exacerbated sensitivity to the interoceptive component of the urge. This is in marked contrast with compulsivity, which will be argued to depend on an inability appropriately to identify the emotional nature of the interoceptive component of the urge. Impulsivity and compulsivity are both associated both with alterations in corticostriatal circuits, especially the insular cortex, and noradrenergic mechanisms in the ventral striatum which may represent a neural switch from impulsive to compulsive behaviours.
Organization SV BMI Hosts: C. Sandi & J. Gräff
Accessibility Informed public