Conferences - Seminars
BMI Seminar // Mitochondrial dynamics and diversity in the mouse nervous system
By Thomas Misgeld, Institute of Neuronal Cell Biology, TUM School of Medicine, Munich, Germany
In my presentation, I will present new approaches to characterize the dynamics and diversity of mitochondria in the nervous system. While many functions have been ascribed to neural mitochondria, how these functions are executed in the in vivo context of vastly extended neuronal geometries remains unresolved. My lab uses in vivo imaging approaches, as well as systemic molecular exploration to understand better (1) how mitochondrial homeostasis is achieved under normal conditions, (2) how it breaks down in disease and (3) how the remarkable specificity of disease manifestations that general mitochondrial defects cause can be explained.
Organization SV BMI Host : Carmen Sandi
Accessibility Informed public