Chemical approaches to sorting out protein post-translational modifications

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Event details

Date 25.07.2016
Hour 16:1518:00
Speaker Prof. Phil A. Cole, Professor and Director of the Department of Pharmacology and Molecular Sciences, School of Medicine, Johns Hopkins University
Location
SV17.17A
Category Conferences - Seminars
Prof. Phil A. Cole uses chemical approaches to study cell signal transduction hormonal control of circadian rhythm and gene regulation. He is interested in understanding the basis for molecular recognition of protein kinases and the mechanism and inhibition of melatonin production via a new protein engineering method called expressed protein ligation. His lab has also developed selective HAT (histone acetyltransferase) and demethylase inhibitors to investigate the role of the protein acetylation and methylation.

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