Computational Design of Self-Assembling Peptides and Proteins

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Event details

Date 06.12.2019
Hour 10:0011:00
Speaker Prof. Ingemar André, Lund University (SE)
Location
Category Conferences - Seminars
BIOENGINEERING SEMINAR    

Abstract:
Many of the largest protein complexes in biology are composed of a single type of subunit that is repeated a large number of times to generate a functional assembly. Such homomeric structures are often assembled spontaneously from individual components through the process of self-assembly. Research in our group is focused on the prediction of the three-dimensional structure of homomeric assemblies and the rational design of novel self-assembling proteins and peptides. I will demonstrate how protein design can be used to develop a self-assembling protein container system for selective encapsulation of proteins. I will also describe the development of a peptide with a pH dependent oligomerization switch, with applications as pH sensitive control elements that can control assembly of larger proteins.

Practical information

  • Informed public
  • Free
  • This event is internal

Tags

protein design Computational Design self-assembling peptides

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