EESS talk on "Biopartitioning of ionic organic chemicals"

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Event details

Date 26.04.2016
Hour 12:1513:15
Speaker Dr Kai-Uwe Goss, Helmholtz Centre (UFZ), Department Analytical Environmental Chemistry, Leipzig, DE
Location
Category Conferences - Seminars
Abstract:
The distribution of organic chemicals in organisms is important for assessing the toxicity of chemicals. Our understanding of these processes is still very fragmentary when it comes to ionic organic chemicals. This talk will a) present experimental and modelling results on the equilibrium partitioning of organic ions to albumin, muscle protein, and membrane lipids; and b) discuss the permeability of ions through biological membranes and how this effects toxicity via the ion trap mechanism and uncoupling

Short biography:
Kai-Uwe Goss studied Geoecology in Bayreuth, Germany. He finished his PhD in environmental chemistry in 1993. This was followed by a 2-year Post-Doc position at the University of Minnesota, USA. The next 10 years he worked at EAWAG and ETH Zürich with Prof. Rene Schwarzenbach. Since 2007 he is heading the Department of Analytical Environmental Chemistry at the Helmholtz Centre for Environmental Research in Leipzig, Germany.

Practical information

  • General public
  • Free
  • This event is internal

Organizer

  • EESS - IIE

Contact

  • Prof. Samuel Arey, LMCE

Tags

biopartitioning membrane permeability modelling ionizable organic chemicals ADME

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