EPFL BioE Talks SERIES "Engineering Next-Generation Drug Delivery Systems for Therapeutic Proteins in Regenerative Medicine and Cancer Immunotherapy"


Event details

Date 28.11.2022
Hour 16:0017:00
Speaker Priscilla Briquez, Assistant Professor, Medical Center, University of Freiburg (DE)
Location Online
Category Conferences - Seminars
Event Language English

Protein engineering is a very powerful tool to improve clinical delivery of therapeutic protein drugs. Indeed, the efficacy of a drug does not only rely on its intrinsic bioactivity, but is also strongly modulated by its interactions within the microenvironment, as well as by its ability to reach the correct receptors and cellular compartments in targeted cells. In this lecture, we will discuss how protein engineering and drug delivery systems can substantially increase therapeutic effects of protein drugs, based on selected examples from regenerative medicine and cancer immunotherapy applications. More specifically, we will focus on the engineering of interactions between growth factors and the extracellular matrix to enhance tissue healing, and the delivery of antigen to improve immunotherapy for melanoma cancer. 

Priscilla Briquez received her master’s degree in Bioengineering from the Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland in 2011. She then continued her studies as a PhD student in the laboratory of Prof. Jeffrey A. Hubbell at EPFL, and specialised herself in protein engineering for applications in regenerative medicine. Her PhD work got awarded by the Institute of Bioengineering Award in 2015 and the EPFL Thesis Award in 2017. During her PhD, Priscilla co-funded and presided the Association of PhD Student in Life Sciences (ADSV, EPFL) and was involved in the school activities as a PhD student representative. After her PhD graduation in 2016, she moved with the Hubbell laboratory in the Institute for Molecular Engineering at University of Chicago (United States of America), where she continued her post-doctoral research in the field of immunoengineering and cancer immunotherapy. Priscilla has recently been appointed as an Assistant Professor at the Medical Center - University of Freiburg in Germany. Her laboratory works in molecular immunoengineering for cancer and regenerative medicine. 

Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks

Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IF you are not attending in-person in the room, please make sure to
  1. send D. Reinhard a note before noon on seminar day, informing that you plan to attend the talk online, and
  2. be signed in on Zoom with a recognizable user name (not a pseudonym making it difficult or impossible to be identified).
Students attending the seminar in-person should collect a confirmation signature after the talk - please print your own signature sheet beforehand (71 kB pdf available for download here).


Practical information

  • Informed public
  • Registration required