EPFL BioE Talks SERIES "High-Throughput and Hi-Dimensional Profiling of Single Antigen-Specific T Cells"
Event details
| Date | 09.10.2023 |
| Hour | 16:00 › 17:00 |
| Speaker | Prof. Jenny Jiang, Department of Bioengineering, University of Pennsylvania, Philadelphia, PA (USA) |
| Location | Online |
| Category | Conferences - Seminars |
| Event Language | English |
WEEKLY EPFL BIOE TALKS SERIES
Abstract:
The recognition of antigens by T cell receptors triggers a series of biological responses by T cells. However, T cell receptors are innately cross-reactive and the collection of T cell receptor repertoire needs to cover a large diverse range of antigens. It has been challenging to understand the relationship between T cell receptor repertoire and antigen repertoire. Recently, Jiang lab has developed several technologies to perform high-throughput and high-dimensional profiling of T cells with a focus of T cell antigen specificity and cross-reactivity. In this talk, she will introduce these technologies and give examples on how they use these technologies to understand the functions of the T cells in several human diseases, which could provide important insights to T cell biology and guide T cell based therapeutic development.
Bio:
Jenny Jiang is a Peter & Geri Skirkanich Associate Professor of Innovation in the Department of Bioengineering at the University of Pennsylvania. She obtained her Ph.D. from Georgia Institute of Technology and did her postdoc training at Stanford University. Dr. Jiang’s research focuses on systems immunology and immune engineering by developing technologies that enable the direct profiling of human immune systems in cancer, infection, and vaccination. Dr. Jiang is a recipient of the prestigious Damon Runyon Cancer Research Foundation Damon Runyon-Rachleff Innovator Award, NSF CAREER Award, and Chan Zuckerberg Initiative Ben Barres Early Career Acceleration award. She is one of the ten National Academy of Medicine 2019 Emerging Leaders in Health and Medicine Scholars and was recently recognized as one of the six 2021 Cancer Research Institute Lloyd J. Old STAR awardees. She is a fellow of the American Institute for Medical and Biological Engineering (AIMBE).
Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks
Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IF you are not attending in-person in the room, please make sure to
Abstract:
The recognition of antigens by T cell receptors triggers a series of biological responses by T cells. However, T cell receptors are innately cross-reactive and the collection of T cell receptor repertoire needs to cover a large diverse range of antigens. It has been challenging to understand the relationship between T cell receptor repertoire and antigen repertoire. Recently, Jiang lab has developed several technologies to perform high-throughput and high-dimensional profiling of T cells with a focus of T cell antigen specificity and cross-reactivity. In this talk, she will introduce these technologies and give examples on how they use these technologies to understand the functions of the T cells in several human diseases, which could provide important insights to T cell biology and guide T cell based therapeutic development.
Bio:
Jenny Jiang is a Peter & Geri Skirkanich Associate Professor of Innovation in the Department of Bioengineering at the University of Pennsylvania. She obtained her Ph.D. from Georgia Institute of Technology and did her postdoc training at Stanford University. Dr. Jiang’s research focuses on systems immunology and immune engineering by developing technologies that enable the direct profiling of human immune systems in cancer, infection, and vaccination. Dr. Jiang is a recipient of the prestigious Damon Runyon Cancer Research Foundation Damon Runyon-Rachleff Innovator Award, NSF CAREER Award, and Chan Zuckerberg Initiative Ben Barres Early Career Acceleration award. She is one of the ten National Academy of Medicine 2019 Emerging Leaders in Health and Medicine Scholars and was recently recognized as one of the six 2021 Cancer Research Institute Lloyd J. Old STAR awardees. She is a fellow of the American Institute for Medical and Biological Engineering (AIMBE).
Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks
Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IF you are not attending in-person in the room, please make sure to
- send D. Reinhard a note before noon on seminar day, informing that you plan to attend the talk online, and
- be signed in on Zoom with a recognizable user name (not a pseudonym making it difficult or impossible to be identified).
Practical information
- Informed public
- Registration required
Organizer
- Prof. Li Tang, EPFL
Contact
- Institute of Bioengineering (IBI), Dietrich REINHARD