From 2 to 4 and then to 2000: how do cells deal with chromosome number increase after whole genome duplications?

After completing a PhD in genetics at the University of Lisbon and the CGM, Gif-sur-Yvette with R. Gomes and R. Karess, Renata Basto moved to the team of Jordan Raff, at the Gurdon Institute, Cambridge UK as a post-doctoral fellow. She studied the consequences of centrosome number alterations in Drosophila. In 2009, she moved to the Cell Biology Department (UMR144) of the Institut Curie in Paris as a junior principal investigator (PI) with a CNRS position. She was promoted senior PI in 2014. R. Basto has been awarded with ERC starting and Consolidator grants, the EMBO YIP fellowship and was elected EMBO member in 2017. Work in her lab addresses the mechanisms leading to genetic instability and the consequences of centrosome and chromosome number alterations in a variety of model systems from Drosophila to human cancers.