How to Make Complex Molecules from Simple Starting Material: the Palladium, a Powerful Tool
Event details
| Date | 27.11.2013 |
| Hour | 17:15 › 18:30 |
| Speaker | Dr. Jean Suffert, Directeur de Recherche at CNRS, Group Leader, Faculté de Pharmacie, Illkirch, France |
| Location | |
| Category | Conferences - Seminars |
In addition to molecular complexity, the challenge of the chemist today is also the quest for efficiency of the synthetic route and maximization of structural complexity. Our laboratory investigations focus for several years on the study of an unprecedented cascade reaction involving a rare 4-exo-dig cyclocarbopalladation followed by a terminated cross-coupling with an organometallic reagent. A 6- or 8-electrocyclization can occur leading to new tricyclic structures. The seminar will show that we can offer an easy access to complex polycyclic molecules resulting from readily available simple starting materials. Eventually, it will be possible to propose the elaboration of a large collection of unprecedented structurally novel molecules based on recent promising results. Below are represented several complex structures that has been prepared through the powerful 4-exo-dig cyclocarbopalladation. Many other extension of this method have not been so far explored and can afford a multitude of new and original scaffolds.
Practical information
- General public
- Free
Organizer
- Prof. Jieping Zhu
[email protected]
Contact
- Prof. Jieping Zhu
[email protected]