Hybrid porous (nano)materials. Confinement and applications
Event details
| Date | 26.11.2014 |
| Hour | 17:15 › 18:15 |
| Speaker | Prof. Luisa de Cola, Institut de Science et d'Ingénieurie Supramoléculaire (ISIS), University of Strasbourg, France and INT-KIT, Karlsruhe, Germany |
| Location | |
| Category | Conferences - Seminars |
Porous systems, and especially those where it is possible to control the chemical composition as well as their size, aspect ratio and pores dimension are of great interest for the development of new materials, catalysis, sensors, biolabels, drug delivery…. The talk will illustrate some of the recent results on inert or active inorganic nanocontainers such as microporous and mesoporous silica based nanoparticles. In particular examples using the crystalline allumino silicates, zeolite L, and mesoporous organosilicates will be discussed since these materials can act as nanocontainers and due to their biocompatibility used for biomedical applications. One of the focuses will be on the properties of molecules, or small metallic clusters entrapped inside the channels. Indeed the organization of molecules or atoms in ordered channels can lead to very special properties absent in any other condition. For example the alignment in 1D of electroactive molecules inside the narrow channels of a zeolite L, resulted in the formation of molecular wires with interesting electrical properties and magnetic behavior [1]. The porous systems can also be functionalized of their surface and it will be shown that the particles can be decorated with different functional groups including biocompatible molecules and are able to perfom drug and PNA delivery inside the cell [2]. The delivery can be probed by kinetic analyses after the nanoparticles internalization. Finally a new strategy to obtain containers that can undergo destruction will be illustrated as a promising approach to clearance of such materials in vivo, independently from their initial size.
References
[1] L. De Cola, W.G. van der Wiel et al. Science, 2013, 341, 257.
[2] R. Corradini, L. De Cola et al Adv. Healthcare Mater. 2014 in press. Chem. Eur. J. in press.
References
[1] L. De Cola, W.G. van der Wiel et al. Science, 2013, 341, 257.
[2] R. Corradini, L. De Cola et al Adv. Healthcare Mater. 2014 in press. Chem. Eur. J. in press.
Practical information
- General public
- Free
Organizer
- Prof. Jérôme Waser
[email protected]
Contact
- Prof. Jérôme Waser
[email protected]