IEM Distinguished Lecturers Seminar: Envisioning the future of computational optical microscopy


Event details

Date 02.06.2023
Hour 13:1514:00
Speaker Prof. Rafael Piestun,
Department of Electrical and Computer Engineering and Department of Physics, University of Colorado Boulder, USA
Location Online
Category Conferences - Seminars
Event Language English
The seminar will take place in ELA 2 and will be simultaneously broadcasted in the main auditorium in Neuchâtel Campus (MC A1 272).

Coffee and cookies will be served at 13:00 before the seminar, in front of the two auditoriums. 

Optical computational imaging seeks enhanced performance and new functionality by the joint design of illumination, unconventional optics, detectors, and reconstruction algorithms. Among the emergent approaches in this field, two remarkable examples enable overcoming the diffraction limit and imaging through complex media.
Overcoming the diffraction resolution limit has enabled unprecedented opportunities for optical imaging at the nanoscale. Fluorescence imaging using photoactivatable or photoswitchable molecules within computational optical systems offers single molecule sensitivity within a wide field of view. The advent of three-dimensional point spread function engineering associated with optimal reconstruction algorithms provides a unique approach to further increase resolution in three dimensions. 
Focusing and imaging through strongly scattering media has also been accomplished recently in the optical regime.  By using a feedback system and fast optical modulation, it is possible to mitigate the effects of multiple scattering upon propagation through the medium. Advanced holographic techniques for phase-control help characterize the scattering media at high-speed using micro-electro-mechanical technology, allowing focusing through a temporally dynamic, strongly scattering sample, or a multimode fiber.
In this talk we explore the prospect of these techniques in biological imaging.
Prof. Rafael Piestun received the Ingeniero Electricista degree from the Universidad de la República (Uruguay) and MSc. and Ph.D. degrees in Electrical Engineering from the Technion – Israel. From 1998 to 2000 he was a researcher at Stanford University. Since 2001 he has been at the University of Colorado Boulder. Professor Piestun is a fellow of the Optical Society of America, was a Fulbright scholar, an Eshkol fellow, received a Honda Initiation Grant award, a Minerva award, a Provost Achievement Award, and El-Op and Gutwirth prizes. He was associate editor of Optics and Photonics News and Applied Optics. He is a co-founder of the company Double Helix Optics (SPIE Prism Award, First Place in the Luminate Competition) and the company Modendo Inc. His areas of interest include computational optical imaging, superresolution microscopy, volumetric photonic devices, scattering optics, and ultrafast optics.