Imaging Spatio-Temporal Signaling Programs Regulating Cell Fate and Cell Morphogenesis
Event details
| Date | 28.11.2017 |
| Hour | 12:15 › 13:00 |
| Speaker | Prof. Olivier Pertz, Institute of Cell Biology, University of Bern (CH) |
| Location | |
| Category | Conferences - Seminars |
BIOENGINEERING SEMINAR
Abstract:
We study spatio-temporal dynamics of signaling regulating cell morphogenesis and cell fate decision at the single cell level. A combination of live cell imaging, microfabrication, computer vision, and mathematical modelling allows us to dissect novel properties of signaling networks, not accessible using classic biochemica/cell biological techniques. I will discuss how robust directional cell migration emerges using a self-organized cytoskeletal module that precisely positions signaling activities in single cells. I will also discuss how one can dissect signaling network architectures that produce dynamic signaling states regulating cell fate decisions such as proliferation or differentiation. This offers new insight to reprogram cell fate decisions at will.
Bio:
Education:
Undergrad studies: Biology, University of Lausanne (CH)
Phd (2009): Biozentrum, University of Basel (CH)
Positions/experience:
Postdoc:
Scripps Institute, La Jolla, CA (USA)
University of California, San Diego, CA (USA)
SNSF Professor (2008): University of Basel (CH)
Associate Professor (2016): University of Bern (CH)
Abstract:
We study spatio-temporal dynamics of signaling regulating cell morphogenesis and cell fate decision at the single cell level. A combination of live cell imaging, microfabrication, computer vision, and mathematical modelling allows us to dissect novel properties of signaling networks, not accessible using classic biochemica/cell biological techniques. I will discuss how robust directional cell migration emerges using a self-organized cytoskeletal module that precisely positions signaling activities in single cells. I will also discuss how one can dissect signaling network architectures that produce dynamic signaling states regulating cell fate decisions such as proliferation or differentiation. This offers new insight to reprogram cell fate decisions at will.
Bio:
Education:
Undergrad studies: Biology, University of Lausanne (CH)
Phd (2009): Biozentrum, University of Basel (CH)
Positions/experience:
Postdoc:
Scripps Institute, La Jolla, CA (USA)
University of California, San Diego, CA (USA)
SNSF Professor (2008): University of Basel (CH)
Associate Professor (2016): University of Bern (CH)
Practical information
- Informed public
- Free
Organizer
Contact
- Institute of Bioengineering (IBI, Dietrich REINHARD)