LCN Seminar: Unlocking the neural code in neurons and neural populations using advanced statistical models and methods

Event details
Date | 09.01.2014 |
Hour | 13:45 › 14:45 |
Speaker | Jonathan PILLOW; Psychology & Neurobiology, The University of Texas at Austin |
Location |
SG 0213
|
Category | Conferences - Seminars |
A major goal of computational neuroscience is to understand how neurons work together to build representations of sensory, motor, and cognitive variables necessary for behavior. A popular approach to this problem is to develop statistical models of the relationship between neural activity and relevant external variables (e.g., sensory stimuli or motor output).
In this talk, I will describe several projects aimed at unlocking the neural code in different brain areas at several different levels of biophysical detail. First, I will describe recent work on characterizing the representation of sensory-motor decisions by neural populations in the lateral intra-parietal cortex (area LIP) in primates. Second, I will describe new methods for rapidly characterizing high-dimensional response properties of single neurons in visual cortex using closed-loop "adaptive" experimental design. Third, I will present a new model-based technique for estimating intracellular excitatory and inhibitory synaptic conductances from extracellular spike trains recorded in primate retina.
I will discuss the implications of these findings for understanding neural codes and the mechanisms by which they are constructed, and the promise of such statistical approaches for gaining insights into neural datasets of increasing size and complexity.
In this talk, I will describe several projects aimed at unlocking the neural code in different brain areas at several different levels of biophysical detail. First, I will describe recent work on characterizing the representation of sensory-motor decisions by neural populations in the lateral intra-parietal cortex (area LIP) in primates. Second, I will describe new methods for rapidly characterizing high-dimensional response properties of single neurons in visual cortex using closed-loop "adaptive" experimental design. Third, I will present a new model-based technique for estimating intracellular excitatory and inhibitory synaptic conductances from extracellular spike trains recorded in primate retina.
I will discuss the implications of these findings for understanding neural codes and the mechanisms by which they are constructed, and the promise of such statistical approaches for gaining insights into neural datasets of increasing size and complexity.
Links
Practical information
- Informed public
- Free
Organizer
- Prof. Wulfram Gerstner
Contact
- Chantal Mellier