Lycopene and adipose tissue biology
Event details
| Date | 04.08.2010 |
| Hour | 10:15 |
| Speaker | Erwan GOURANTON, lab “Lipid nutrients & prevention metabolic diseases (UMR 1260 INRA/476 INSERM ), Marseille, France |
| Location | |
| Category | Conferences - Seminars |
Adipose tissue is a complex organ which exerts several metabolic functions. It is involved in the regulation of the energy balance and since a decade is well known as an exocrine organ which secrets several proteins collectively called adipokines such as adiponectin, leptin… It is one of the main organs involved in obesity where it concentrates several cellular dysfunctions which will have important physiological consequences such as development of insulin resistance, type II diabetes and cardiovascular diseases.
Epidemiological studies have reported that high consumption of fruits and vegetables is link to a decrease of pathologies such as cardiovascular diseases, type II diabetes and cancer; due to the presence of micronutrients notably carotenoids. Among these carotenoids, lycopene and β-carotene play an important role. They are the main carotenoids in our diet, and are physiologically store in adipose tissue. Furthermore, others studies point that the high consumption or concentration of these compounds in adipose tissue is associated to a decrease of the risk to develop cardiovascular diseases. Moreover, it has been recently reported that higher lycopene intakes were associated with a lower waist circumference and visceral and subcutaneous fat mass, suggesting its impact on adipose tissue metabolism.
However, the link between carotenoids, adipose tissue, obesity-associated pathologies is unclear. The presentation will focus on the effect of lycopene and metabolites on several aspect of the biology of adipose tissue, which could be considered as particularly relevant in the context of obesity-associated pathologies.
Practical information
- General public
- Free