Making Multi-Cell Patterns Interactive, Accessible, and Programmable: Biotic Games, Biophysics Cloud labs, and Synthetic Cell-Cell Adhesion
Event details
| Date | 27.09.2017 |
| Hour | 10:30 › 11:30 |
| Speaker | Prof. Ingmar H. Riedel-Kruse, Stanford University, Stanford, CA (USA) |
| Location | |
| Category | Conferences - Seminars |
BIOENGINEERING SEMINAR
Abstract:
Modern biotechnology gets increasingly powerful to manipulate and measure microscopic biological processes. Nevertheless, no platform exists to truly interact and program with these processes, certainly not with the convenience that we are accustomed to from our electronic smart devices. I will provide the rational for such “Interactive Bio-Technology” and conceptualize biotic processing unit (BPUs). I will demonstrate multiple platforms based on photo-tactic Euglena cells, e.g., biotic video games, scalable biology cloud experimentation labs, tangible museum exhibits, and swarm programming languages. I will demonstrate how we can expand the reach of synthetic biology towards multicellular structures: an orthogonal set of genetically encoded heterophilic cell-cell adhesion pairs enables self-assembled patterns at the 5 um scale. Optogenetic control of homophilic cell-cell adhesion enables the programming of biofilm patterns at the 100 um scale. Applications of our work aim to advance smart-materials science, STEM education, and the scientific method.
Bio:
Ingmar H. Riedel-Kruse is an Assistant Professor of Bioengineering at Stanford University. His lab focuses on Interactive Bio-Technology, Cloud labs, and Multi-Cell Biophysics. He received his Diploma in Theoretical Physics at the Technical University Dresden, did his PhD in experimental biophysics at the Max Planck Institute for Molecular Cell Biology and Genetics, followed by a postdoc at Caltech.
EDUCATION:
2001-2005 PhD with Prof. Jonathon Howard (co-advisor: Prof. Frank Jülicher)
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Biophysics: Collective phenomena, molecular motors, sperm cells, hydrodynamics
1995-2000 Diploma in physics with Prof. Ingrid Mertig
Technical University Dresden, Germany
Theoretical solid-state physics: Ab initio calculations, electronic band structures, quantum transport
EXPERIENCE:
2006-2009 Postdoc (“Beckman fellow”) with Prof. Gilles Laurent
California Institute of Technology, Pasadena, USA
Systems neurobiology: Dynamics and coding in olfactory systems
2005-2006 Postdoc with Dr. Andrew Oates
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Developmental biology: Oscillatory genetic networks in zebrafish somitogenesis
2001 Business consultant
ACCENTURE, Düsseldorf, Germany
Strategic consulting: Option pricing and risk-management in electricity trading
Abstract:
Modern biotechnology gets increasingly powerful to manipulate and measure microscopic biological processes. Nevertheless, no platform exists to truly interact and program with these processes, certainly not with the convenience that we are accustomed to from our electronic smart devices. I will provide the rational for such “Interactive Bio-Technology” and conceptualize biotic processing unit (BPUs). I will demonstrate multiple platforms based on photo-tactic Euglena cells, e.g., biotic video games, scalable biology cloud experimentation labs, tangible museum exhibits, and swarm programming languages. I will demonstrate how we can expand the reach of synthetic biology towards multicellular structures: an orthogonal set of genetically encoded heterophilic cell-cell adhesion pairs enables self-assembled patterns at the 5 um scale. Optogenetic control of homophilic cell-cell adhesion enables the programming of biofilm patterns at the 100 um scale. Applications of our work aim to advance smart-materials science, STEM education, and the scientific method.
Bio:
Ingmar H. Riedel-Kruse is an Assistant Professor of Bioengineering at Stanford University. His lab focuses on Interactive Bio-Technology, Cloud labs, and Multi-Cell Biophysics. He received his Diploma in Theoretical Physics at the Technical University Dresden, did his PhD in experimental biophysics at the Max Planck Institute for Molecular Cell Biology and Genetics, followed by a postdoc at Caltech.
EDUCATION:
2001-2005 PhD with Prof. Jonathon Howard (co-advisor: Prof. Frank Jülicher)
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Biophysics: Collective phenomena, molecular motors, sperm cells, hydrodynamics
1995-2000 Diploma in physics with Prof. Ingrid Mertig
Technical University Dresden, Germany
Theoretical solid-state physics: Ab initio calculations, electronic band structures, quantum transport
EXPERIENCE:
2006-2009 Postdoc (“Beckman fellow”) with Prof. Gilles Laurent
California Institute of Technology, Pasadena, USA
Systems neurobiology: Dynamics and coding in olfactory systems
2005-2006 Postdoc with Dr. Andrew Oates
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Developmental biology: Oscillatory genetic networks in zebrafish somitogenesis
2001 Business consultant
ACCENTURE, Düsseldorf, Germany
Strategic consulting: Option pricing and risk-management in electricity trading
Practical information
- Informed public
- Free
Organizer
Contact
- Institute of Bioengineering (IBI, Dietrich REINHARD)