[ MICHAEL J. FOX FOUNDATION - Assay Development and Validation for Quantifying Oligomeric Alphasynuclein | Research funding ]

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Event details

Date 19.04.2019
Category Call for proposal
Aim: The Michael J. Fox Foundation will award one-year grants for research to advance the development, optimization and validation of assays to quantify oligomeric alpha-synuclein in human body fluids. These biofluids may include blood, cerebrospinal fluid, saliva and tears. Prior research suggests that alpha-synuclein quantification in accessible body fluids may serve as a biomarker of disease diagnosis, target engagement, pharmacodynamic response and/or patient stratification.
  • Immuno-assays should have a renewable source of the antibodies used. Optimization and/or adaptation of existent assays to different biological matrices will also be considered.
  • Projects should propose to develop or optimize assays with superior performance in quantifying oligomeric alpha-synuclein and, at the end of the grant, should be able to present several performance parameters for further validation such as robustness, precision, trueness, uncertainty, limits of detection and quantification, dilutional linearity, parallelism, recovery, selectivity, and sample stability.
 
Funding:        Maximum USD $200’000
                       
Duration:      12 months
                       
Eligibility: Researchers at all academic levels at or above Assistant Professor are eligible to apply. Post-doctoral fellows are eligible to apply as co-investigators with the designation of an administrative primary investigator who directs the laboratory in which the fellow will conduct research.
 
How to Apply: The pre-proposal is the first step in the application. Pre-proposals must be completed in the online application portal.  Successful applicants will be given further instructions for submitting a full proposal.
 
Deadline (Pre-proposal): 19 April 2019 (5:00 pm EST)
Deadline (Full Application, by invitation): 19 July 2019 (5:00 pm EST)
 
Further information
  • See the official webpage for more details, or download the RFA
  • Find the application portal here
  • Participate in the MJFF funding opportunities webinar on 01 April to learn more
  • For any other questions, contact the Research Office: [email protected]

Practical information

  • General public
  • Free

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