Microtechnologies to Map the Fate of Single Stem Cells and their Progeny

Event details
Date | 27.04.2012 |
Hour | 17:30 › 20:00 |
Speaker | Stefan A. Kobel |
Location | |
Category | Thesis defenses |
Current in vitro systems are not only very inefficient in tracking and studying single stem cells over time, but also they cannot distinguish the fate of the daughter cells generated by these single cells. This thesis addresses some of these shortcomings by developing miniaturized devices to handle and analyze single live stem cells.
My presentation will describe a micro-structured platform to passively capture and culture single hematopoietic stem cells and several microfluidic modules to actively trap and manipulate single cells, physically separate their daughter cells and to analyze the gene expression of single cells.
The further integration of such microfluidic modules into multi-functional lab-on-a-chip devices will open the door to novel experimental paradigms and promises novel insights in stem cell biology.
The presentation will be followed by an aperitif.
My presentation will describe a micro-structured platform to passively capture and culture single hematopoietic stem cells and several microfluidic modules to actively trap and manipulate single cells, physically separate their daughter cells and to analyze the gene expression of single cells.
The further integration of such microfluidic modules into multi-functional lab-on-a-chip devices will open the door to novel experimental paradigms and promises novel insights in stem cell biology.
The presentation will be followed by an aperitif.
Practical information
- General public
- Free