Mining microbial dark matter for drug development

Thumbnail

Event details

Date 04.11.2014
Hour 16:1517:15
Speaker Prof. Jörn Piel, ETH Zürich, Switzerland
Location
SV1717A
Category Conferences - Seminars
Culturable bacteria provide many bioactive natural products that serve as an important basis for drug development. By extrapolation it has been proposed that the great diversity of as-yet unculturable prokaryotes represents a massive discovery resource for novel drug candidates. However, little functional insights existed about the metabolic potential of these organisms. This talk summarizes recent findings derived from metagenomic, single-cell, and biochemical studies that reveal members of the microbiota in marine sponges and other macroorganisms as extraordinarily rich producers of structurally distinct, potent bioactives. The results open attractive avenues for drug discovery and targeted studies on the ecological role of microbiomes.

Practical information

  • General public
  • Free

Organizer

Contact

Event broadcasted in

Share