Modulation of Tumor Stroma to Potential Immune Checkpoint Blockade Therapy
Event details
| Date | 01.06.2018 |
| Hour | 14:30 |
| Speaker | Prof. Chun Li, The University of Texas MD Anderson Cancer Center, Houston, TX (USA) |
| Location | |
| Category | Conferences - Seminars |
BIOENGINEERING SEMINAR
Abstract:
Poly(L-glutamic acid)-paclitaxel (PG-TXL) represents a few of nano-formulations that had reached the stage of phase III clinical trials. This talk will provide an overview of the preclinical and clinical evaluations of PG-TXL, and discuss lessons learned from this ordeal. While reflecting on issues concerning clinical translation of nano-formulations, this talk will provide future perspectives on nanotechnology, exemplified by both pharmacological and physical approaches to modulate tumor stroma and enhance immune checkpoint blockade therapy.
Bio:
Present Title & Affiliation:
Abstract:
Poly(L-glutamic acid)-paclitaxel (PG-TXL) represents a few of nano-formulations that had reached the stage of phase III clinical trials. This talk will provide an overview of the preclinical and clinical evaluations of PG-TXL, and discuss lessons learned from this ordeal. While reflecting on issues concerning clinical translation of nano-formulations, this talk will provide future perspectives on nanotechnology, exemplified by both pharmacological and physical approaches to modulate tumor stroma and enhance immune checkpoint blockade therapy.
Bio:
Present Title & Affiliation:
- Professor, Department of Cancer Systems Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
- Adjunct Professor, Department of College of Pharmacy, University of Houston, Houston, TX
- Faculty, Division of Graduate School of Biological Sciences, Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, TX
- 1983: BS, Chemistry - Peking University (CHN)
- 1991-1993: Research Associate, The University of Texas MD Anderson Cancer Center, Houston, TX (USA)
- 1991: PHD, Chemistry - Rutgers-The State University of New Jersey, New Brunswick, NJ (USA)
- 2011 - 2016: Adjunct Professor, Department of Biomedical Engineering and Nanomedicine, The University of Texas Health Science Center at Houston, Houston, TX
- 2010 - 2016: Adjunct Professor, Department of PET Center, Zhejiang University, Hangzhou
- 2005 - 2007: Adjunct Associate Professor, Department of Dept. of Bioengineering, Rice University, Houston, TX
- 2002 - 2005: Adjunct Associate Professor, Department of Dept. of Chemical Engineering, Texas A&M University, College Station, TX
- 2000 - 2003: Associate Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
- 1994 - 2000: Assistant Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
- 1993 - 1994: Instructor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Practical information
- Informed public
- Free
Organizer
Contact
- Institute of Bioengineering (IBI, Dietrich REINHARD)