Novel Determinants of the Hematopoietic Microenvironment in Development and Homeostasis
Event details
| Date | 09.01.2009 |
| Hour | 13:30 |
| Speaker | Dr. Olaia Naveiras |
| Location |
AI 1 153
|
| Category | Conferences - Seminars |
Seminar of the Institute of Bioengineering
Abstract:
The promise of regenerative medicine depends on succeeding at generating sufficient amounts of functional, transplantable tissue by reliably differentiating pluripotent stem cells through the paths of ontogeny, or by efficiently expanding adult stem cells in vitro. For that purpose, the environmental cues responsible for cell fate decisions in vivo need to be deciphered and reproduced in vitro. We have focused on the hematopoietic system as the best characterized stem cell model system, and present here two novel modulators of the embryonic and adult hematopoietic microenvironment: biomechanical forces, and specifically shear stress, as hematopoietic determinants in the developing aorta, and bone marrow adipocytes as negative regulators of the hematopoietic milieu.
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Practical information
- General public
- Free
Contact
- M. Lütolf (3 18 76)