‘On-Water’ Catalysis: Mechanism and Synthetic Applications

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Event details

Date 14.11.2012
Hour 17:1518:30
Speaker Prof. C. S. P. McErlean
School of Chemistry, The University of Sydney, Australia
Location
Category Conferences - Seminars
Of all the solvents used in organic synthesis, water is uniquely advantageous. It is environmentally benign, non-flammable, liquid over a wide temperature range and possesses a high heat capacity which makes it inherently safe. Water also possesses the remarkable ability to catalyse chemical transformations between some insoluble organic reactants, a phenomenon known as “on-water catalysis”.1,2 This seminar will detail some of our recent studies to uncover the mechanism responsible for this unique form of catalysis. This knowledge allows us to develop on-water catalysed processes for the synthesis of medicinally relevant architectures.3-5 





1. Narayan, S.; Muldoon, J.; Finn, M. G.; Fokin, V. V.; Kolb, H. C.; Sharpless, K. B. Angewandte Chemie-International Edition 2005, 44, 3275.
2. Beattie, J. K.; McErlean, C. S. P.; Phippen, C. B. W. Chemistry - A European Journal 2010, 16, 8972.
3. Phippen, C. B. W.; Beattie, J. K.; McErlean, C. S. P. Chemical Communications 2010, 46, 8234.
4. Phippen, C. B. W.; McErlean, C. S. P. Tetrahedron Letters 2011, 52, 1490.
5. Norcott, P.; Spielman, C.; McErlean, C. S. P. Green Chemistry 2012, 14, 605.

Practical information

  • General public
  • Free

Organizer

  • Hosted by Prof. Jieping Zhu

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