Probing protein dynamics by intrinsic tryptophan
Event details
| Date | 26.11.2012 |
| Hour | 15:00 › 16:00 |
| Speaker | Prof. Dongping Zhong |
| Location | |
| Category | Conferences - Seminars |
Tryptophan has the longest wavelength absorption among other amino acids and has recently been used as an optical probe of protein dynamics on ultrafast time scales. Here, by combing femtosecond spectroscopy and site-directed mutagenesis, we have carried out a series of studies including ultrafast protein electron transfer, resonance energy transfer, conformation fluctuations, and water-protein coupled motions, and observed various nonequilibrium protein dynamics with femtosecond temporal and single-residue spatial resolutions. These studies demonstrated that tryptophan is a powerful molecular probe and can be widely used for probing ultrafast protein dynamics on the most fundamental level.
Practical information
- Informed public
- Free
- This event is internal
Organizer
- Prof. Majed Chergui