RIG-I like receptors and autoimmune diseases

Event details
Date | 06.05.2016 |
Hour | 14:00 |
Speaker | Hiroki Kato, Institute for Virus Research, Kyoto University |
Location | |
Category | Conferences - Seminars |
RIG-I-like receptors (RLRs) are well-known viral sensors that trigger the antiviral interferon (IFN) response by recognizing the non-self signatures of viral RNAs. The proper induction of the IFN response is known to play a crucial role in protecting against viral infections, whereas aberrant activation can lead to autoimmune disorders. I will give a brief introduction on RLR-mediated antiviral response and mainly talk about the antiviral IFN response and autoimmunity, with a focus on recent studies describing autoimmunity caused by mutations in RLRs.
Practical information
- Informed public
- Free
Organizer
- Prof. Andrea Ablasser