Seminar "Bio/Nano/CMOS interfaces for Remote Monitoring of Human Metabolism", by Dr. Sandro Carrara
Event details
| Date | 30.09.2019 |
| Hour | 10:15 › 11:30 |
| Speaker | Dr. Sandro Carrara |
| Location | |
| Category | Conferences - Seminars |
The Institute of Microengineering is pleased to invite you to Dr. Sandro Carrara's seminar titled "Bio/Nano/CMOS interfaces for Remote Monitoring of Human Metabolism"
This lecture is part of the Distinguished Lectures Program of the IEEE Sensors Council
On Monday September 30, 2019
10:15 – Room SV1717
Videoconference is organized in Neuchâtel campus, room MC B0 302
Possibility to follow the seminar by remote via zoom: https://epfl.zoom.us/j/405196262
Abstract:
The development of circuits and systems as integrated with electrochemical nanobiosensors for the monitoring and diagnosis of patients with specific metabolic conditions (e.g., heart failures, cardiovascular illnesses, cancer diseases) or convalescents at home is a key factor to succeed in providing better, more rationale, effective, and ultimately low-cost technologies for personalized and precision medicine. The development of implantable and/or wearable medical-IoT (Internet of Things for medical applications) is the right way to bring easy-to-use monitoring devices available to this aim. However, there are no so-far-available integrated nano-bio-systems for the continuous and remote monitoring of the human metabolism at multi-metabolites level. In fact, many IoT systems available in the market are proposing the use of devices such as accelerometers, ECG monitors (for electrocardiogram monitoring), and other sensors that are usually not suitable for monitoring the human metabolism at molecular level (e.g., to measure cell metabolites). The only implantable or wearable systems available for real-time control of the human metabolism are limited to glucose monitoring, while electrochemical sensors may address so many other endogenous and exogenous molecules that are of crucial relevance in human metabolism of many diseases as well as in the monitoring of chronic patients or critical patients. Thus, the aim of this distinguished lecture of the IEEE Sensors Council Program is to present innovative concepts for developing devices for the continuous monitoring of human metabolism at molecular level by using multi-panel, highly integrated, fully implantable, and remotely powered systems. More specifically, the considered metabolic molecules will be: glucose, lactate, glutamate, and ATP as models of endogenous metabolites; cyclophosphamide, benzphetamine, propofol, paracetamol, and midazolam as models of therapeutic compounds; and potassium as a model of metabolic ions. Examples of applications to point-of-care devices (e.g., for the monitoring in intensive care units [1]), implantable systems [2], and wearable medical-IoT will be then demonstrated. Future perspectives about injectable or diffusible diagnostic devices in the form of Smart Dust [3] will be finally discussed as well.
[1] https://actu.epfl.ch/news/monitoring-critical-blood-levels-in-real-time-in-t/
[2] https://actu.epfl.ch/news/a-chip-placed-under-the-skin-for-more-precise-medi/
[3] https://actu.epfl.ch/news/tracking-cancer-cell-development-with-drinkable-el/
About the speaker:
Sandro Carrara is an IEEE Fellow and also the recipient of the IEEE Sensors Council Technical Achievement Award. He is faculty at the EPFL in Lausanne (Switzerland), and former professor at the Universities of Genoa and Bologna (Italy). He holds a PhD in Biochemistry and Biophysics, a Master degree in Physics, and a diploma in Electronics. His scientific interests are on electrical phenomena of nano-bio-structured films, and include CMOS design of biochips based on proteins and DNA. Along his carrier, he published 7 books, one as author in 2013 with Springer about Bio/CMOS interfaces and, more recently, a Handbook of Bioelectronics with Cambridge University Press. He has more than 270 scientific publications and is author of 14 patents. He is now Editor-in-Chief of the IEEE Sensors Journal, the largest among 180 IEEE publications, founder and Editor-in-Chief of the journal BioNanoScience by Springer, and Associate Editor of IEEE Transactions on Biomedical Circuits and Systems. He is a member of the IEEE Sensors Council, and was a member of the Board of Governors (BoG) of the IEEE CAS Society. He has been appointed two times as Distinguished Lecturer of IEEE. His work received several international recognitions as best-cited papers and as best conference papers. He has been the General Chairman of the Conference IEEE BioCAS 2014, a premier worldwide conference in the area of circuits and systems for biomedical, and General Co-Chair of the Conferences IEEE MeMeA 2018, the IEEE international symposium on medical measurements and applications, and PRIME 2019, the conference on PhD research in microelectronics and electronics.
This lecture is part of the Distinguished Lectures Program of the IEEE Sensors Council
On Monday September 30, 2019
10:15 – Room SV1717
Videoconference is organized in Neuchâtel campus, room MC B0 302
Possibility to follow the seminar by remote via zoom: https://epfl.zoom.us/j/405196262
Abstract:
The development of circuits and systems as integrated with electrochemical nanobiosensors for the monitoring and diagnosis of patients with specific metabolic conditions (e.g., heart failures, cardiovascular illnesses, cancer diseases) or convalescents at home is a key factor to succeed in providing better, more rationale, effective, and ultimately low-cost technologies for personalized and precision medicine. The development of implantable and/or wearable medical-IoT (Internet of Things for medical applications) is the right way to bring easy-to-use monitoring devices available to this aim. However, there are no so-far-available integrated nano-bio-systems for the continuous and remote monitoring of the human metabolism at multi-metabolites level. In fact, many IoT systems available in the market are proposing the use of devices such as accelerometers, ECG monitors (for electrocardiogram monitoring), and other sensors that are usually not suitable for monitoring the human metabolism at molecular level (e.g., to measure cell metabolites). The only implantable or wearable systems available for real-time control of the human metabolism are limited to glucose monitoring, while electrochemical sensors may address so many other endogenous and exogenous molecules that are of crucial relevance in human metabolism of many diseases as well as in the monitoring of chronic patients or critical patients. Thus, the aim of this distinguished lecture of the IEEE Sensors Council Program is to present innovative concepts for developing devices for the continuous monitoring of human metabolism at molecular level by using multi-panel, highly integrated, fully implantable, and remotely powered systems. More specifically, the considered metabolic molecules will be: glucose, lactate, glutamate, and ATP as models of endogenous metabolites; cyclophosphamide, benzphetamine, propofol, paracetamol, and midazolam as models of therapeutic compounds; and potassium as a model of metabolic ions. Examples of applications to point-of-care devices (e.g., for the monitoring in intensive care units [1]), implantable systems [2], and wearable medical-IoT will be then demonstrated. Future perspectives about injectable or diffusible diagnostic devices in the form of Smart Dust [3] will be finally discussed as well.
[1] https://actu.epfl.ch/news/monitoring-critical-blood-levels-in-real-time-in-t/
[2] https://actu.epfl.ch/news/a-chip-placed-under-the-skin-for-more-precise-medi/
[3] https://actu.epfl.ch/news/tracking-cancer-cell-development-with-drinkable-el/
About the speaker:
Sandro Carrara is an IEEE Fellow and also the recipient of the IEEE Sensors Council Technical Achievement Award. He is faculty at the EPFL in Lausanne (Switzerland), and former professor at the Universities of Genoa and Bologna (Italy). He holds a PhD in Biochemistry and Biophysics, a Master degree in Physics, and a diploma in Electronics. His scientific interests are on electrical phenomena of nano-bio-structured films, and include CMOS design of biochips based on proteins and DNA. Along his carrier, he published 7 books, one as author in 2013 with Springer about Bio/CMOS interfaces and, more recently, a Handbook of Bioelectronics with Cambridge University Press. He has more than 270 scientific publications and is author of 14 patents. He is now Editor-in-Chief of the IEEE Sensors Journal, the largest among 180 IEEE publications, founder and Editor-in-Chief of the journal BioNanoScience by Springer, and Associate Editor of IEEE Transactions on Biomedical Circuits and Systems. He is a member of the IEEE Sensors Council, and was a member of the Board of Governors (BoG) of the IEEE CAS Society. He has been appointed two times as Distinguished Lecturer of IEEE. His work received several international recognitions as best-cited papers and as best conference papers. He has been the General Chairman of the Conference IEEE BioCAS 2014, a premier worldwide conference in the area of circuits and systems for biomedical, and General Co-Chair of the Conferences IEEE MeMeA 2018, the IEEE international symposium on medical measurements and applications, and PRIME 2019, the conference on PhD research in microelectronics and electronics.
Practical information
- General public
- Free
- This event is internal
Organizer
- Institute of Microengineering - EPFL STI IMT