Thiol-based Redox Signaling
Event details
| Date | 13.10.2020 |
| Hour | 16:15 › 18:00 |
| Speaker | Prof. Tobias P. Dick (DKFZ, Heidelberg) |
| Location | |
| Category | Conferences - Seminars |
COMPULSORY REGISTRATION - DEADLINE OCTOBER 9TH, 2020
Redox signaling is a process by which endogenous oxidants, derived from metabolism, reversibly modify particular thiols on particular proteins to change their functional behavior in an adaptive manner. However, the molecular mechanisms of redox signaling remain largely unknown. In many cases, specificity and efficiency of redox signaling remain unexplained. An emerging solution to this conundrum is that redox signaling can be mediated and channeled by protein-to-protein redox relay chains. There is growing evidence that H2O2 signals are relayed through thiol peroxidases to neighboring proteins within supramolecular assemblies.
Redox signaling is a process by which endogenous oxidants, derived from metabolism, reversibly modify particular thiols on particular proteins to change their functional behavior in an adaptive manner. However, the molecular mechanisms of redox signaling remain largely unknown. In many cases, specificity and efficiency of redox signaling remain unexplained. An emerging solution to this conundrum is that redox signaling can be mediated and channeled by protein-to-protein redox relay chains. There is growing evidence that H2O2 signals are relayed through thiol peroxidases to neighboring proteins within supramolecular assemblies.
Practical information
- General public
- Free
Organizer
- NCCR Lecture Series
Contact
- Marie Munoz