What we can (not) learn from high-throughput data and sequence analysis of protein-DNA interactions: from sequence motifs to regulatory variants and back
Event details
| Date | 25.02.2020 |
| Hour | 12:00 › 13:00 |
| Speaker | Ivan Kulakovskiy, Engelhardt Institute of Molecular Biology and Vavilov Institute of General Genetics of Moscow |
| Location | |
| Category | Conferences - Seminars |
This presentation will start by introducing several software tools for sequence motif analysis developed by the autosome.ru team. Next, it will be shown how the presented tools can be used for practical analysis of eukaryotic gene regulation. In particular, the construction of a systematic collection of motifs representing transcription factor binding sites will be discussed, together with the annotation of single-nucleotide variants in gene regulatory regions. Finally, we shall have a sneak peek at an ongoing large-scale meta-analysis of ChIP-Seq data to discover allele-specific transcription factor binding events.
Practical information
- Expert
- Free
- This event is internal
Organizer
- Philipp Bucher