Conferences - Seminars
Workshop: "Debugging and Evolving Artificial Metalloenzymes: Chemical and Biological Challenges"
By Thomas R. Ward, Professor at the University of Basel and Director of NCCR Molecular Systems Engineering and Dr. Tillmann Heinisch, senior researcher in the Ward group. Thomas Ward is a pioneer of artificial metalloenzymes, developing systems for synthetic biology, bio-nanotechnology and white biotechnology. His academic career is focused on understanding and harnessing catalysis, as well as combining homogeneous and enzymatic catalysis in bio-organic chemistry. Thomas Ward is currently working towards realizing his DrEAM: the Directed Evolution of Artificial Metalloenzymes.
Tillmann Heinisch is a senior researcher in the group of Prof. Ward (UniBas), in collaboration with Prof. Panke (ETH Zurich). Dr. Heinisch is currently working on strategies to expand the faction scope of natural E. coli metabolic pathways by the unique chemistries of artificial metalloenzymes.
“Directed evolution of artificial metalloenzymes for in vivo metathesis”, M. Jeschek, R. Reuter, T. Heinisch, C. Trindler, J. Klehr, S. Panke, T. R. Ward, Nature, 2016, 537, 661.
“Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology: Challenges and Opportunities”, T. Heinisch, T. R. Ward, Acc. Chem. Res., 2016, 49, 1711.
The workshop is associated with the NCCR lecture series hosted by NCCR junior scientists to provide insights into theoretical and practical aspects of artificial enzyme catalysis. Extended time for discussion will allow sharing on these issues.
Please register here (deadline May 19). Limited number of seats!
The workshop follows the talk given by Thomas R. Ward on “Endowing Organometallic Chemistry with a Genetic Memory”, EPFL: May 30 - BCH 3118 - 11:15.
Organization NCCR Chemical Biology
Admittance Registration required