Event List
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{ "count": 238, "next": "https://memento.epfl.ch/api/v1/events/?format=api&limit=10&offset=10&ordering=-event__url_place_and_room", "previous": null, "results": [ { "id": 58478, "title": "EPFL - MicroNanoFabrication Annual Review Meeting", "slug": "epfl-micronanofabrication-annual-review-meeting-3", "event_url": "https://memento.epfl.ch/event/epfl-micronanofabrication-annual-review-meeting-3", "visual_url": "https://memento.epfl.ch/image/20782/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/20782/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/20782/max-size.jpg", "lang": "en", "start_date": "2026-05-12", "end_date": "2026-05-12", "start_time": "09:00:00", "end_time": "18:00:00", "description": "<strong>EPFL - MicroNanoFabrication Annual Review Meeting</strong><br>\r\n<em>The Networking Forum</em><br>\r\n<em>- presenting research achievements of the past year<br>\r\n- encouraging interaction among professors, researchers, students, and industry partners</em><br>\r\n- <em>25th edition<br>\r\n<br>\r\n<strong>EARLY ANNOUNCEMENT</strong></em><br>\r\n<br>\r\nDate : Tuesday May 12th, 2026<br>\r\nTime : 09h00 - 18h00<br>\r\nPlace : SwissTech Convention Center<br>\r\nEvent website : <a href=\"https://cmi-events.epfl.ch/\">https://cmi-events.epfl.ch/</a><br>\r\n<br>\r\nProgram :<br>\r\n- 10 invited speakers (<a href=\"https://cmi-events.epfl.ch/events/annual-review-2026/program\">Program</a>)<br>\r\n- 200 posters presented by the authors<br>\r\n- 30 exhibition booths<br>\r\n<br>\r\nThe posters show the research projects realized during the last 12 months in the EPFL Center of MicroNanoTechnology (CMi).<br>\r\n<br>\r\nThe scope of the forum is <em>Micro & Nano Fabrication Techniques</em> used in the following fields:<br>\r\n <br>\r\n- Nanostructure Physics (VCSELs, Quantum Opto-Electronics, III/V Devices, Nanotubes, Nanowires, Nanomechanics, ...)<br>\r\n- Quantum sciences ant technology (quantum opto- electro- mechanics, superconducting devices, QDs, sensors, circuits)<br>\r\n- Micro and Nanoelectronics (Soft Bioelectronic, 3D Integration, Nanowires, High-Q Resonators, New materials, ...)<br>\r\n- Biomedical Applications (Microfluidics, Microelectrodes, Lab on a Chip, Probes, Neuroprosthetics, ...)<br>\r\n- MEMS, NEMS (Sensors and Actuators, Motors, Tweezers, Artificial Muscles, Micro and Nanomechanics, ...)<br>\r\n- Optics (Nanophotonics, Optomechanics, Photonic Crystals, MOEMS, Optofluidics, Fibers, ...)<br>\r\n- Material Sciences (Photovoltaic Materials, Piezoelectric materials, Nanoparticles, Energy Harvesting, Micro Fuel Cells, ...)<br>\r\n- Fabrication Technologies (Lithography, Etching, Thin Films, ALD, EBEAM, CMP, Self assembly, Inkjet Printing, PDMS, ...)<br>\r\n- Metrology and Defect Analysis (SEM, FIB, Ellipsometry, Reflectometry, AFM, EDX, Stress, Conductivity, ...)<br>\r\n- Packaging and Assembly (Grinding, Wire Bonding, Encapsulation, ...)<br>\r\n<br>\r\nMore than 600 people attended the previous editions, including :<br>\r\n- professors,<br>\r\n- industrials,<br>\r\n- researchers,<br>\r\n- students.<br>\r\n<br>\r\n<strong>Registration on : <a href=\"https://cmi-events.epfl.ch/\">https://cmi-events.epfl.ch/</a></strong><br>\r\n<br>\r\n<em>The meeting is organized by the EPFL Center of MicroNanoTechnology (CMi).</em><br>\r\n<br>\r\n<em>Dr Philippe Flückiger<br>\r\nDirector of Operations</em><br>\r\n<em><a href=\"http://cmi.epfl.ch/\">http://cmi.epfl.ch/</a></em><br>\r\n<em>Phone +41 21 693 6695</em>", "image_description": "", "creation_date": "2022-01-13T15:41:36", "last_modification_date": "2026-03-03T16:31:29", "link_label": "", "link_url": "https://www.epfl.ch/research/facilities/cmi/", "canceled": "False", "cancel_reason": "", "place_and_room": "SwissTech Convention Center", "url_place_and_room": "https://www.stcc.ch/", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "10 invited speakers", "organizer": "EPFL Center of MicroNanoTechnology (CMi)", "contact": "[email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/100934/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/377/?format=api" ] }, { "id": 70203, "title": "Coding Club for Girls in St. Gallen", "slug": "coding-club-for-girls-in-st-gallen-7", "event_url": "https://memento.epfl.ch/event/coding-club-for-girls-in-st-gallen-7", "visual_url": "https://memento.epfl.ch/image/31703/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/31703/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/31703/max-size.jpg", "lang": "en", "start_date": "2026-04-29", "end_date": "2026-05-06", "start_time": "13:30:00", "end_time": "16:00:00", "description": "<p>Eine App programmieren? Ein Computerspiel erfinden? Eine Animation gestalten?<br>\r\nWenn dich eines dieser Dinge interessiert, bist du hier am richtigen Ort! Tausche und teile deine Ideen, lerne zu programmieren und entdecke Informatikberufe.<br>\r\n<br>\r\nDie <a href=\"https://www.epfl.ch/education/education-and-science-outreach/de/jugendliche/coding-club/\">Coding Club for Girls</a> Workshops sind für Mädchen im Alter von 11 bis 15 Jahren und die Teilnahme ist kostenlos. Ab der Teilnahme an vier Workshops pro Jahr wird eine Teilnahmebestätigung ausgehändigt. <br>\r\n<br>\r\n<strong>Ort:</strong> Smartfeld, St. Gallen<br>\r\n<br>\r\n<strong>Datum und Zeit:</strong><br>\r\n<strong>Mittwoch, 29. April 2026 : 13:30 bis 16:00 Uhr // Mit Computern chatten</strong><br>\r\n<strong>Mittwoch, 06. Mai 2026 : 13:30 bis 16:00 Uhr // Aktion Internet</strong><br>\r\n<br>\r\nDie Inhalte der Workshops sind untenstehend beschrieben.<br>\r\n<br>\r\n<strong>Bedingungen</strong>\r\n</p><ul>\r\n\t<li>Gratis</li>\r\n\t<li><a href=\"https://forms.gle/xY45W6G9Q9o9JC168\">Anmeldung unter diesem Link </a></li>\r\n\t<li><a href=\"https://www.epfl.ch/education/education-and-science-outreach/de/teilnahmebedingungen/\">Allgemeine Teilnahmebedingungen EPFL - SPS Aktivitäten</a> </li>\r\n</ul>\r\n<strong>Workshops:<br>\r\nMit Computern chatten - Mittwoch, 29. April 2026</strong><br>\r\nComputer haben ihre eigene Sprache. Dank diesem Workshop wirst du lernen, mit einem Mikro-Computer zu kommunizieren, damit er macht, was du möchtest! Hilf uns einfache Programme zu debuggen und ein Spiel für zwei Spielerinnen zu entwerfen. <br>\r\n<br>\r\n<strong>Aktion Internet - Mittwoch, 06. Mai 2026</strong><br>\r\nDas Internet ist weitläufig und voller Informationen. Wie kannst du schnell Antworten auf deine Fragen finden? Bei diesem Workshop lernst du Suchmaschinen zu beherrschen und du wirst einer virtuellen Escape Room entkommen.<br>\r\n<br>\r\n<a href=\"https://forms.gle/xY45W6G9Q9o9JC168\"><strong>Anmeldung</strong></a><br>\r\n ", "image_description": "", "creation_date": "2025-10-24T10:54:09", "last_modification_date": "2025-12-09T09:54:48", "link_label": "Anmeldung", "link_url": "https://forms.gle/xY45W6G9Q9o9JC168", "canceled": "False", "cancel_reason": "", "place_and_room": "Smartfeld, St. Gallen", "url_place_and_room": "https://www.smartfeld.ch/kontakt/", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/3/?format=api" ], "speaker": "", "organizer": "<a href=\"https://www.epfl.ch/education/education-and-science-outreach/fr/index-fr-html/promotion-des-sciences/\">A</a><a href=\"https://www.epfl.ch/education/education-and-science-outreach/de/wissenschaftsfoerderung/\">bteilung für Wissenschaftsförderung (SPS) der EPFL</a> ", "contact": "<a href=\"mailto:[email protected]\">[email protected]</a>", "is_internal": "False", "theme": "", "vulgarization": { "id": 1, "fr_label": "Tout public", "en_label": "General public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "Coding Club for Girls, Deutsch, SPS, Jugendliche, St. Gallen, SG", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/118269/", "category": { "id": 18, "code": "YOUTHSCIENCE", "fr_label": "Activités scientifiques pour les jeunes", "en_label": "Sciences Activities for Youth", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/170/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api" ] }, { "id": 70956, "title": "G protein-coupled receptors functional dynamics revealed by experimental and computational structural data", "slug": "g-protein-coupled-receptors-functional-dynamics-re", "event_url": "https://memento.epfl.ch/event/g-protein-coupled-receptors-functional-dynamics-re", "visual_url": "https://memento.epfl.ch/image/32345/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/32345/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/32345/max-size.jpg", "lang": "en", "start_date": "2026-10-07", "end_date": "2026-10-09", "start_time": null, "end_time": null, "description": "<p>You can apply to participate and find all the relevant information (speakers, abstracts, program,...) on the event website: <a href=\"https://www.cecam.org/workshop-details/g-protein-coupled-receptors-functional-dynamics-revealed-by-experimental-and-computational-structural-data-1488\">https://www.cecam.org/workshop-details/g-protein-coupled-receptors-functional-dynamics-revealed-by-experimental-and-computational-structural-data-1488</a>.<br>\r\n<br>\r\nRegistration is required to attend the full event, take part in the social activities and present a poster at the poster session (if any). However, the EPFL community is welcome to attend specific lectures without registration if the topic is of interest to their research. Do not hesitate to contact the <a href=\"mailto:[email protected]\">CECAM Event Manager</a> if you have any question.<br>\r\n<br>\r\n<strong>Description</strong><br>\r\n<br>\r\nG protein-coupled receptors (GPCRs) represent a vast and diverse class of transmembrane proteins that orchestrate a wide range of physiological processes by responding to both endogenous and exogenous ligands [1,2]. These receptors are essential to critical functions such as metabolism, immune regulation, neuronal signaling, and sensory perception - including vision and olfaction. Due to their physiological relevance and membrane accessibility, GPCRs are the targets of approximately 34% of all prescribed medications, accounting for nearly 27% of the global pharmaceutical market [3]. <br>\r\nDespite their pharmaceutical importance, key aspects of GPCR function remain elusive. The canonical activation model posits that agonist binding to the extracellular orthosteric site triggers allosteric changes - most notably, the outward displacement of transmembrane helices 5 (TM5) and 6 (TM6) on the intracellular side - ultimately leading to receptor activation [2-4]. However, recent evidence suggests a more nuanced mechanism. In several GPCRs, activation appears to involve cooperative engagement between the agonist and the G protein. For example, the G protein may disrupt an \"inactivating ionic lock\" - a salt bridge between TM3 and TM6 - while the agonist stabilizes the active conformation. In some receptors, this is complemented by the formation of an “activating ionic lock” between TM5 and TM6 [5-8]. These dual contributions are considered thermodynamically essential for full activation [7].<br>\r\nAdding further complexity, GPCR activity is regulated by conformational microswitches and finely tuned intra-protein interaction networks. These dynamic rearrangements are difficult to capture and often elude direct correlation with functional outcomes. Moreover, allosteric ligands - which bind sites distinct from the orthosteric pocket - are being increasingly identified [9-12], along with small molecules capable of biased signaling, i.e., preferential activation of specific intracellular pathways [11-13, 16, 17]. These findings reveal a rich and underexplored conformational landscape that governs GPCR signaling. In addition, native membrane components—such as lipids and interacting proteins, including GPCR oligomers—are known to significantly modulate receptor function [11, 18-22].<br>\r\nTo disentangle these intricacies, computational modeling has become indispensable, offering atomistic insight into GPCR conformational dynamics and mechanistic understanding [1-2, 7, 11, 14, 16–21, 23]. Nevertheless, key questions remain - particularly regarding the structural basis of biased signaling, strategies for leveraging allosteric networks in pharmacology, and the modulatory role of the lipid environment. Addressing these gaps is crucial for both fundamental biology and the rational design of next-generation GPCR-targeting drugs with improved selectivity and safety profiles. <br>\r\nThese scientific challenges form the foundation of our upcoming workshop, which will focus on the latest experimental and computational approaches for studying the functional dynamics of GPCRs. Given the profound health, economic, and societal implications of modulating these receptors with precision, we aim to strengthen the interdisciplinary nature of the event by increasing the representation of experimental research and integrating cutting-edge artificial intelligence applications into the program.<br>\r\nBuilding upon the success of the 2022 and 2024 editions - which led to new collaborations and a landmark publication in <em>Nature Reviews Drug Discovery</em> [24] - our goal is to further enhance communication and collaboration between experimentalists and theoreticians. The workshop will serve as a reference point for young scientists and students, offering a platform to interact with leading international experts. We are confident that this initiative will foster insightful discussions and contribute meaningfully to advancing the field of GPCR pharmacology.<br>\r\n<br>\r\n<strong>References</strong><br>\r\n<br>\r\n<a href=\"https://doi.org/10.1038/nrd.2017.229\" target=\"_blank\">[1] J. Smith, R. Lefkowitz, S. Rajagopal, Nat. Rev. Drug. Discov., <strong>17</strong>, 243-260 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41573-024-01083-3\" target=\"_blank\">[2] P. Conflitti, E. Lyman, M. Sansom, P. Hildebrand, H. Gutiérrez-de-Terán, P. Carloni, T. Ansell, S. Yuan, P. Barth, A. Robinson, C. Tate, D. Gloriam, S. Grzesiek, M. Eddy, S. Prosser, V. Limongelli, Nat. Rev. Drug. Discov., <strong>24</strong>, 251-275 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41589-024-01682-6\" target=\"_blank\">[3] L. Picard, A. Orazietti, D. Tran, A. Tucs, S. Hagimoto, Z. Qi, S. Huang, K. Tsuda, A. Kitao, A. Sljoka, R. Prosser, Nat. Chem. Biol., <strong>21</strong>, 71-79 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.drudis.2020.10.006\" target=\"_blank\">[4] B. Huang, C. St. Onge, H. Ma, Y. Zhang, Drug Discovery Today, <strong>26</strong>, 189-199 (2021)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41467-023-42082-z\" target=\"_blank\">[5] D. Di Marino, P. Conflitti, S. Motta, V. Limongelli, Nat. Commun., <strong>14</strong>, 6439 (2023)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.ceb.2018.10.007\" target=\"_blank\">[6] G. Milligan, R. Ward, S. Marsango, Current Opinion in Cell Biology, <strong>57</strong>, 40-47 (2019)</a><br>\r\n<a href=\"https://doi.org/10.7554/elife.73901\" target=\"_blank\">[7] S. Huang, O. Almurad, R. Pejana, Z. Morrison, A. Pandey, L. Picard, M. Nitz, A. Sljoka, R. Prosser, eLife, <strong>11</strong>, (2022)</a><br>\r\n<a href=\"https://doi.org/10.1146/annurev-pharmtox-010919-023411\" target=\"_blank\">[8] A. Duncan, W. Song, M. Sansom, Annu. Rev. Pharmacol. Toxicol., <strong>60</strong>, 31-50 (2020)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41467-025-60003-0\" target=\"_blank\">[9] A. Morales-Pastor, T. Miljuš, M. Dieguez-Eceolaza, T. Stępniewski, V. Ledesma-Martin, F. Heydenreich, T. Flock, B. Plouffe, C. Le Gouill, J. Duchaine, D. Sykes, C. Nicholson, E. Koers, W. Guba, A. Rufer, U. Grether, M. Bouvier, D. Veprintsev, J. Selent, Nat. Commun., <strong>16</strong>, 5265 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41586-022-05588-y\" target=\"_blank\">[10] A. Faouzi, H. Wang, S. Zaidi, J. DiBerto, T. Che, Q. Qu, M. Robertson, M. Madasu, A. El Daibani, B. Varga, T. Zhang, C. Ruiz, S. Liu, J. Xu, K. Appourchaux, S. Slocum, S. Eans, M. Cameron, R. Al-Hasani, Y. Pan, B. Roth, J. McLaughlin, G. Skiniotis, V. Katritch, B. Kobilka, S. Majumdar, Nature, <strong>613</strong>, 767-774 (2022)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41467-022-31652-2\" target=\"_blank\">[11] M. Wall, E. Hill, R. Huckstepp, K. Barkan, G. Deganutti, M. Leuenberger, B. Preti, I. Winfield, S. Carvalho, A. Suchankova, H. Wei, D. Safitri, X. Huang, W. Imlach, C. La Mache, E. Dean, C. Hume, S. Hayward, J. Oliver, F. Zhao, D. Spanswick, C. Reynolds, M. Lochner, G. Ladds, B. Frenguelli, Nat. Commun., <strong>13</strong>, 4150 (2022)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41580-018-0049-3\" target=\"_blank\">[12] D. Wootten, A. Christopoulos, M. Marti-Solano, M. Babu, P. Sexton, Nat. Rev. Mol. Cell. Biol., <strong>19</strong>, 638-653 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41594-017-0011-7\" target=\"_blank\">[13] D. Hilger, M. Masureel, B. Kobilka, Nat. Struct. Mol. Biol., <strong>25</strong>, 4-12 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41467-025-57034-y\" target=\"_blank\">[14] D. Aranda-García, T. Stepniewski, M. Torrens-Fontanals, A. García-Recio, M. Lopez-Balastegui, B. Medel-Lacruz, A. Morales-Pastor, A. Peralta-García, M. Dieguez-Eceolaza, D. Sotillo-Nuñez, T. Ding, M. Drabek, C. Jacquemard, J. Jakowiecki, W. Jespers, M. Jiménez-Rosés, V. Jun-Yu-Lim, A. Nicoli, U. Orzel, A. Shahraki, J. Tiemann, V. Ledesma-Martin, F. Nerín-Fonz, S. Suárez-Dou, O. Canal, G. Pándy-Szekeres, J. Mao, D. Gloriam, E. Kellenberger, D. Latek, R. Guixà-González, H. Gutiérrez-de-Terán, I. Tikhonova, P. Hildebrand, M. Filizola, M. Babu, A. Di Pizio, S. Filipek, P. Kolb, A. Cordomi, T. Giorgino, M. Marti-Solano, J. Selent, Nat. Commun., <strong>16</strong>, 2020 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41586-018-0259-z\" target=\"_blank\">[15] D. Thal, A. Glukhova, P. Sexton, A. Christopoulos, Nature, <strong>559</strong>, 45-53 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.tips.2020.12.005\" target=\"_blank\">[16] L. Slosky, M. Caron, L. Barak, Trends in Pharmacological Sciences, <strong>42</strong>, 283-299 (2021)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.apsb.2023.07.020\" target=\"_blank\">[17] C. Zhu, X. Lan, Z. Wei, J. Yu, J. Zhang, Acta Pharmaceutica Sinica B, <strong>14</strong>, 67-86 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.chempr.2024.08.004\" target=\"_blank\">[18] V. D’Amore, P. Conflitti, L. Marinelli, V. Limongelli, Chem, <strong>10</strong>, 3678-3698 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41557-023-01238-6\" target=\"_blank\">[19] A. Mafi, S. Kim, W. Goddard, Nat. Chem., <strong>15</strong>, 1127-1137 (2023)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41594-024-01334-2\" target=\"_blank\">[20] H. Batebi, G. Pérez-Hernández, S. Rahman, B. Lan, A. Kamprad, M. Shi, D. Speck, J. Tiemann, R. Guixà-González, F. Reinhardt, P. Stadler, M. Papasergi-Scott, G. Skiniotis, P. Scheerer, B. Kobilka, J. Mathiesen, X. Liu, P. Hildebrand, Nat. Struct. Mol. Biol., <strong>31</strong>, 1692-1701 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.cell.2015.04.043\" target=\"_blank\">[21] A. Manglik, T. Kim, M. Masureel, C. Altenbach, Z. Yang, D. Hilger, M. Lerch, T. Kobilka, F. Thian, W. Hubbell, R. Prosser, B. Kobilka, Cell, <strong>161</strong>, 1101-1111 (2015)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.cell.2020.03.003\" target=\"_blank\">[22] M. Congreve, C. de Graaf, N. Swain, C. Tate, Cell, <strong>181</strong>, 81-91 (2020)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41573-025-01139-y\" target=\"_blank\">[23] J. Lorente, A. Sokolov, G. Ferguson, H. Schiöth, A. Hauser, D. Gloriam, Nat. Rev. Drug. Discov., <strong>24</strong>, 458-479 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1111/bph.16495\" target=\"_blank\">[24] M. Lopez‐Balastegui, T. Stepniewski, M. Kogut‐Günthel, A. Di Pizio, M. Rosenkilde, J. Mao, J. Selent, British. J. Pharmacology., <strong>182</strong>, 3211-3224 (2024)</a>\r\n</p><div class=\"active tab-pane\"> </div>", "image_description": "", "creation_date": "2026-01-26T16:00:31", "last_modification_date": "2026-01-26T16:45:08", "link_label": "G protein-coupled receptors functional dynamics revealed by experimental and computational structura", "link_url": "https://www.cecam.org/workshop-details/g-protein-coupled-receptors-functional-dynamics-revealed-by-experimental-and-computational-structural-data-1488", "canceled": "False", "cancel_reason": "", "place_and_room": "Aula Magna, USI Lugano", "url_place_and_room": "https://www.desk.usi.ch/en/lugano-campus-map-access-facilities", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "", "organizer": "<strong>Vittorio Limongelli</strong>, Università della Svizzera Italiana USI Lugano ; <strong>Scott Prosser</strong>, University of Toronto ; <strong>Stefano Raniolo</strong>, Università della Svizzera Italiana ; <strong>Jana Selent</strong>, Hospital Del Mar Medical Research Institute", "contact": "<a href=\"mailto:[email protected]\"><strong>Cornelia Bujenita</strong></a>, CECAM Events and Operations Manager", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/119453/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/5/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/27/?format=api" ] }, { "id": 70957, "title": "From Data to Dynamics: Machine Learning in Statistical Mechanics and Molecular Simulations", "slug": "from-data-to-dynamics-machine-learning-in-statis-2", "event_url": "https://memento.epfl.ch/event/from-data-to-dynamics-machine-learning-in-statis-2", "visual_url": "https://memento.epfl.ch/image/32346/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/32346/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/32346/max-size.jpg", "lang": "en", "start_date": "2026-10-14", "end_date": "2026-10-16", "start_time": null, "end_time": null, "description": "<p>You can apply to participate and find all the relevant information (speakers, abstracts, program,...) on the event website: <a href=\"https://www.cecam.org/workshop-details/from-data-to-dynamics-machine-learning-in-statistical-mechanics-and-molecular-simulations-1487\">https://www.cecam.org/workshop-details/from-data-to-dynamics-machine-learning-in-statistical-mechanics-and-molecular-simulations-1487</a>.<br>\r\n<br>\r\nRegistration is required to attend the full event, take part in the social activities and present a poster at the poster session (if any). However, the EPFL community is welcome to attend specific lectures without registration if the topic is of interest to their research. Do not hesitate to contact the <a href=\"mailto:[email protected]\">CECAM Event Manager</a> if you have any question.<br>\r\n<br>\r\n<strong>Description</strong><br>\r\nSince its introduction in the 1970s, molecular dynamics (MD) has become an indispensable computational microscope for studying complex biological systems at atomic resolution. It has enabled detailed investigations into protein folding, conformational dynamics, and ligand binding and unbinding. Over the past decade, increasing computational power has made microsecond-scale simulations routine, producing massive datasets that demand sophisticated analysis strategies [1]. Despite these advances, conventional MD simulations still face a fundamental limitation: many biologically relevant events occur over milliseconds to seconds—timescales largely inaccessible to standard MD.<br>\r\nTo bridge this gap, researchers increasingly turn to enhanced sampling techniques—such as metadynamics and umbrella sampling [2,3]—and coarse-grained (CG) modeling approaches [4]. These methods enable more comprehensive exploration of the system’s free energy landscape, yet their success critically depends on the selection of appropriate reaction coordinates or collective variables (CVs). CVs must capture the slowest, most functionally relevant motions to accurately reflect thermodynamic and kinetic behavior. However, identifying suitable CVs remains one of the field’s most challenging tasks, typically requiring domain expertise and iterative refinement [5, 6].<br>\r\nThis complexity has fueled growing interest in machine learning (ML) techniques, which are now transforming how MD simulations are analyzed, interpreted, and even conducted. ML methods have been applied to automate CV discovery, perform dimensionality reduction, build thermodynamic and kinetic models, and enhance sampling efficiency [7]. These models often employ artificial neural networks or graph neural networks to map high-dimensional molecular configurations—such as Cartesian coordinates or molecular descriptors—into low-dimensional representations suitable for analysis [8].<br>\r\nDepending on the structure and type of data, ML algorithms can be broadly categorized into supervised, unsupervised, and reinforcement learning paradigms [9]. Supervised learning uses labeled input-output pairs to predict properties such as molecular energies or binding affinities [10], while unsupervised learning enables the identification of latent features, such as CVs, directly from data [11].<br>\r\nA cornerstone of modern ML-driven simulation is the development of symmetry-aware molecular representations. The predictive power of ML models hinges on encoding physical symmetries—like rotation and translation—directly into the model. E(3)-equivariant neural networks have emerged as powerful tools for this purpose, significantly improving data efficiency and generalization in learning potential energy surfaces [12]. Ongoing research continues to explore the optimal balance between enforcing strict symmetry and retaining model flexibility.<br>\r\nMeanwhile, breakthroughs in structural prediction—most notably the advent of AlphaFold 3—have revolutionized how researchers obtain initial molecular configurations. AlphaFold now provides remarkably accurate models of not only proteins but also their complexes with nucleic acids, ions, and small-molecule ligands [13]. However, these are static snapshots. They cannot capture dynamic behaviors, allosteric transitions, or binding kinetics—areas where physics-based simulations remain indispensable. Initial benchmarks suggest that even state-of-the-art predictors still fall short in modeling protein dynamics and ranking ligand binding affinities, further emphasizing the role of MD [14].<br>\r\nTo address the dimensionality and sampling bottlenecks, unsupervised ML approaches such as time-lagged autoencoders have reframed CV identification as a data-driven task. More recently, generative models—including diffusion models and variational autoencoders—have emerged as a new frontier. These models can learn the full conformational landscape of biomolecules and enable enhanced sampling, in some cases eliminating the need for predefined CVs altogether [15].<br>\r\nOnce accurate structural models and CVs are established, ML can significantly improve the estimation of thermodynamic and kinetic properties. In drug discovery, for instance, predicting protein–ligand binding affinity remains a central challenge. ML potentials trained on quantum mechanical data can be combined with enhanced sampling to yield highly accurate free energy landscapes and binding kinetics—results previously unattainable due to computational limitations [16]. However, challenges in data quality, model interpretability, and transferability remain critical areas of ongoing investigation [17].<br>\r\nFinally, ML is driving a renaissance in CG modeling. Deep neural networks can now learn many-body CG potentials directly from all-atom simulations, capturing emergent properties and enhancing transferability [18]. These models open the door to longer, larger-scale simulations with greater physical accuracy.<br>\r\nIn this rapidly evolving context, it becomes imperative to critically assess both the promise and limitations of ML in biomolecular simulation. The excitement surrounding these developments must be tempered by careful validation and benchmarking. This workshop thus serves as a timely opportunity—especially for early-career researchers—to explore these cutting-edge methods, engage in constructive dialogue, and chart new directions in the application of machine learning to molecular dynamics and drug discovery.<br>\r\n <br>\r\n<strong>References</strong><br>\r\n<br>\r\n<a href=\"https://doi.org/10.1103/physrevlett.98.146401\" target=\"_blank\">[1] J. Behler, M. Parrinello, Phys. Rev. Lett., <strong>98</strong>, 146401 (2007)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.sbi.2024.102972\" target=\"_blank\">[2] P. Sahrmann, G. Voth, Current Opinion in Structural Biology, <strong>90</strong>, 102972 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1021/acs.jcim.2c01127\" target=\"_blank\">[3] K. Kříž, L. Schmidt, A. Andersson, M. Walz, D. van der Spoel, J. Chem. Inf. Model., <strong>63</strong>, 412-431 (2023)</a><br>\r\n<a href=\"https://doi.org/10.3389/fmolb.2022.899805\" target=\"_blank\">[4] K. Ahmad, A. Rizzi, R. Capelli, D. Mandelli, W. Lyu, P. Carloni, Front. Mol. Biosci., <strong>9</strong>, (2022)</a><br>\r\n<a href=\"https://doi.org/10.1146/annurev-physchem-083122-125941\" target=\"_blank\">[5] S. Mehdi, Z. Smith, L. Herron, Z. Zou, P. Tiwary, Annual Review of Physical Chemistry, <strong>75</strong>, 347-370 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1101/2025.04.07.647682\" target=\"_blank\">[6] H. Zheng, H. Lin, A. Alade, J. Chen, E. Monroy, M. Zhang, J. Wang, AlphaFold3 in Drug Discovery: A Comprehensive Assessment of Capabilities, Limitations, and Applications, 2025</a><br>\r\n<a href=\"https://doi.org/10.1038/s41586-024-07487-w\" target=\"_blank\">[7] J. Abramson, J. Adler, J. Dunger, R. Evans, T. Green, A. Pritzel, O. Ronneberger, L. Willmore, A. Ballard, J. Bambrick, S. Bodenstein, D. Evans, C. Hung, M. O’Neill, D. Reiman, K. Tunyasuvunakool, Z. Wu, A. Žemgulytė, E. Arvaniti, C. Beattie, O. Bertolli, A. Bridgland, A. Cherepanov, M. Congreve, A. Cowen-Rivers, A. Cowie, M. Figurnov, F. Fuchs, H. Gladman, R. Jain, Y. Khan, C. Low, K. Perlin, A. Potapenko, P. Savy, S. Singh, A. Stecula, A. Thillaisundaram, C. Tong, S. Yakneen, E. Zhong, M. Zielinski, A. Žídek, V. Bapst, P. Kohli, M. Jaderberg, D. Hassabis, J. Jumper, Nature, <strong>630</strong>, 493-500 (2024)</a><br>\r\n[8] Fabian B. Fuchs, Daniel E. Worrall, Volker Fischer, Max Welling, NIPS'20: Proceedings of the 34th International Conference on Neural Information Processing Systems, Article No.: 166, Pages 1970 - 1981 (2020)<br>\r\n<a href=\"https://doi.org/10.1080/00268976.2020.1737742\" target=\"_blank\">[9] H. Sidky, W. Chen, A. Ferguson, Molecular Physics, <strong>118</strong>, (2020)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.sbi.2019.12.016\" target=\"_blank\">[10] Y. Wang, J. Lamim Ribeiro, P. Tiwary, Current Opinion in Structural Biology, <strong>61</strong>, 139-145 (2020)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41586-018-0337-2\" target=\"_blank\">[11] K. Butler, D. Davies, H. Cartwright, O. Isayev, A. Walsh, Nature, <strong>559</strong>, 547-555 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1146/annurev-physchem-042018-052331\" target=\"_blank\">[12] F. Noé, A. Tkatchenko, K. Müller, C. Clementi, Annu. Rev. Phys. Chem., <strong>71</strong>, 361-390 (2020)</a><br>\r\n<a href=\"https://doi.org/10.1080/23746149.2021.2006080\" target=\"_blank\">[13] S. Kaptan, I. Vattulainen, Advances in Physics: X, <strong>7</strong>, (2022)</a><br>\r\n<a href=\"https://doi.org/10.1002/wcms.1455\" target=\"_blank\">[14] V. Limongelli, WIREs. Comput. Mol. Sci., <strong>10</strong>, (2020)</a><br>\r\n<a href=\"https://doi.org/10.1021/acs.chemrev.0c01195\" target=\"_blank\">[15] A. Glielmo, B. Husic, A. Rodriguez, C. Clementi, F. Noé, A. Laio, Chem. Rev., <strong>121</strong>, 9722-9758 (2021)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.sbi.2018.11.005\" target=\"_blank\">[16] A. Pak, G. Voth, Current Opinion in Structural Biology, <strong>52</strong>, 119-126 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1021/jacs.6b05602\" target=\"_blank\">[17] M. Lelimousin, V. Limongelli, M. Sansom, J. Am. Chem. Soc., <strong>138</strong>, 10611-10622 (2016)</a><br>\r\n<a href=\"https://doi.org/10.3390/e16010163\" target=\"_blank\">[18] C. Abrams, G. Bussi, Entropy, <strong>16</strong>, 163-199 (2013)</a>\r\n</p><div class=\"active tab-pane\"> </div>", "image_description": "", "creation_date": "2026-01-26T16:07:22", "last_modification_date": "2026-01-26T16:45:31", "link_label": "From Data to Dynamics: Machine Learning in Statistical Mechanics and Molecular Simulations", "link_url": "https://www.cecam.org/workshop-details/from-data-to-dynamics-machine-learning-in-statistical-mechanics-and-molecular-simulations-1487", "canceled": "False", "cancel_reason": "", "place_and_room": "Aula Magna, USI Lugano", "url_place_and_room": "https://www.desk.usi.ch/en/lugano-campus-map-access-facilities", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "", "organizer": "<strong>Daniele Angioletti, </strong>Università della Svizzera Italiana (USI) ; <strong>Vincenzo Maria D'Amore, </strong>University of Naples \"Federico II\" ; <strong>Marco De Vivo, </strong>Istituto Italiano di Tecnologia ; <strong>Francesco Saverio Di Leva, </strong>University of Naples Federico II ; <strong>Vittorio Limongelli, </strong>Università della Svizzera Italiana USI Lugano ; <strong>Gregory Voth, </strong>University of Chicago", "contact": "<a href=\"mailto:[email protected]\"><strong>Cornelia Bujenita</strong></a>, CECAM Events and Operations Manager", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/119454/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/5/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/27/?format=api" ] }, { "id": 70201, "title": "Coding Club for Girls in Basel", "slug": "coding-club-for-girls-in-basel-8", "event_url": "https://memento.epfl.ch/event/coding-club-for-girls-in-basel-8", "visual_url": "https://memento.epfl.ch/image/31712/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/31712/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/31712/max-size.jpg", "lang": "en", "start_date": "2026-04-18", "end_date": "2026-05-02", "start_time": "09:30:00", "end_time": "16:00:00", "description": "<p>Eine App programmieren? Ein Computerspiel erfinden? Eine Animation gestalten?<br>\r\nWenn dich eines dieser Dinge interessiert, bist du hier am richtigen Ort! Tausche und teile deine Ideen, lerne zu programmieren und entdecke Informatikberufe.<br>\r\n<br>\r\nDie <a href=\"https://www.epfl.ch/education/education-and-science-outreach/de/jugendliche/coding-club/\">Coding Club for Girls</a> Workshops sind für Mädchen im Alter von 11 bis 15 Jahren und die Teilnahme ist kostenlos. Ab der Teilnahme an vier Workshops pro Jahr wird eine Teilnahmebestätigung ausgehändigt. <br>\r\n<br>\r\n<strong>Ort:</strong> Schulhaus Brunnmatt<strong>, </strong>Basel<br>\r\n<br>\r\n<strong>Datum und Zeit:</strong><br>\r\n<strong>18. April 2026 : 09:30 bis 12:00 oder 13:30 bis 16:00 Uhr // Mit Computern chatten<br>\r\n25. April 2026 </strong><strong>: 09:30 bis 12:00 oder 13:30 bis 16:00 Uhr // Aktion Internet<br>\r\n02. Mai 2026 : 09:30 bis 12:00 oder 13:30 bis 16:00 Uhr // Hello 3D World</strong><br>\r\n<br>\r\nDie Inhalte der Workshops sind untenstehend beschrieben.<br>\r\n<br>\r\n<strong>Bedingungen</strong>\r\n</p><ul>\r\n\t<li>Gratis</li>\r\n\t<li><a href=\"https://forms.gle/2umcR87G6GRLVER48\">Anmeldung unter diesem Link </a></li>\r\n\t<li><a href=\"https://www.epfl.ch/education/education-and-science-outreach/de/teilnahmebedingungen/\">Allgemeine Teilnahmebedingungen EPFL - SPS Aktivitäten</a> </li>\r\n</ul>\r\n<strong>Workshops:</strong><br>\r\n<strong>Mit Computern chatten - Samstag, 18. April 2026</strong><br>\r\nComputer haben ihre eigene Sprache. Dank diesem Workshop wirst du lernen, mit einem Mikro-Computer zu kommunizieren, damit er macht, was du möchtest! Hilf uns einfache Programme zu debuggen und ein Spiel für zwei Spielerinnen zu entwerfen. <br>\r\n<br>\r\n<strong>Aktion Internet - Samstag, 25. April 2026</strong><br>\r\nDas Internet ist weitläufig und voller Informationen. Wie kannst du schnell Antworten auf deine Fragen finden? Bei diesem Workshop lernst du Suchmaschinen zu beherrschen und du wirst einer virtuellen Escape Room entkommen.<br>\r\n<br>\r\n<strong>Hello 3D World - Samstag, 2. Mai 2026</strong><br>\r\nWie denkst du wurden die Figuren und Kulissen in den Filmen Shrek, Cars, Ice Age oder Kung Fu Panda gestaltet? Beim Entwerfen und Animieren von 3D-Objekten kannst Du wie im richtigen Animationsstudio gleichzeitig in die Rolle einer Künstlerin und einer Informatikerin schlüpfen. Du wirst dreidimensionale Objekte rund um das Thema Wald gestalten und in einem zweiten Schritt deiner Fantasie freien Lauf lassen und deine eigenen 3D-Objekte entwerfen!<br>\r\n<br>\r\n<br>\r\n<a href=\"https://forms.gle/2umcR87G6GRLVER48\"><strong>Anmeldung</strong></a><br>\r\n ", "image_description": "", "creation_date": "2025-10-24T10:33:01", "last_modification_date": "2025-12-02T10:25:44", "link_label": "Anmeldung", "link_url": "https://forms.gle/2umcR87G6GRLVER48", "canceled": "False", "cancel_reason": "", "place_and_room": "Schulhaus Brunnmatt, Ingelsteinweg 6, 4053 Basel", "url_place_and_room": "https://schulen.edubs.ch/ps/brunnmatt/", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/3/?format=api" ], "speaker": "", "organizer": "<a href=\"https://www.epfl.ch/education/education-and-science-outreach/fr/index-fr-html/promotion-des-sciences/\">A</a><a href=\"https://www.epfl.ch/education/education-and-science-outreach/de/wissenschaftsfoerderung/\">bteilung für Wissenschaftsförderung (SPS) der EPFL</a> ", "contact": "[email protected] ", "is_internal": "False", "theme": "", "vulgarization": { "id": 1, "fr_label": "Tout public", "en_label": "General public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "Coding Club for Girls, Deutsch, SPS, Jugendliche, Basel, BS", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/118266/", "category": { "id": 18, "code": "YOUTHSCIENCE", "fr_label": "Activités scientifiques pour les jeunes", "en_label": "Sciences Activities for Youth", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/170/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api" ] }, { "id": 67916, "title": "REGARD: Design your future: How to make professional choices (day 2/2)", "slug": "regard-design-your-future-how-to-make-profession-4", "event_url": "https://memento.epfl.ch/event/regard-design-your-future-how-to-make-profession-4", "visual_url": "https://memento.epfl.ch/image/29532/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/29532/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/29532/max-size.jpg", "lang": "en", "start_date": "2026-05-11", "end_date": "2026-05-18", "start_time": "09:00:00", "end_time": "17:00:00", "description": "<strong>Prerequisite</strong><br>\r\nParticipants are required to participate in the two days of the workshop, that will be held on <u><strong>September 1 </strong></u>and <u><strong>September 15</strong></u><br>\r\n<br>\r\n<strong>Target audience </strong>Female PhD candidates and advanced researchers<br>\r\n<br>\r\n<strong>Content</strong><br>\r\nIn all professions including academic careers, satisfaction and a sense of fulfillment are not always at hand, leading sometimes to questioning professional choices. Are you unsure of what is professionally right for you? Have you wondered how you could find it out which profession or career will make you feel truly fulfilled? Do you lack orientation to decide on the next step in your career?<br>\r\nIn this workshop, you will be provided with proven orientation models and tools that will guide you in your career decisions. We will implement them. They are based on an authenticity-oriented perspective aiming at a fulfilling work and self-realisation experience.<br>\r\nWorkshop objectives\r\n<ul>\r\n\t<li>You understand what is the formula for sustainable satisfaction and fulfilment in your profession</li>\r\n\t<li>You obtain tools to find a reliable and secure orientation in your professional life</li>\r\n\t<li>You understand that you can achieve your potential through different career models</li>\r\n\t<li>You get knowledge about how to increase your own competitiveness in the field</li>\r\n</ul>\r\n<strong>Programme</strong>\r\n\r\n<ul>\r\n\t<li>A proposed model on which to base our professional choices</li>\r\n\t<li>Talents, strengths and values</li>\r\n\t<li>The different career styles</li>\r\n\t<li>Your personal career design</li>\r\n</ul>\r\n<strong>Methods</strong><br>\r\nInteractive, practical and reflexive seminar comprising group, pair and individual exercises, plenary discussions, body work, personal preparatory and process work between the dates, coaching via e-mail, feedback, as well as theoretical input on the relevant topics.<br>\r\n<br>\r\n<strong>Participants</strong><br>\r\nThe program is tailored to PhD candidates, postdoctoral fellows & senior scientists who wish to experience fulfillment and self-realization in their career, and wish to acquire and practice tools that will enable them to reach that goal.<br>\r\n ", "image_description": "", "creation_date": "2024-12-19T16:00:18", "last_modification_date": "2024-12-19T16:14:07", "link_label": "Information et inscription", "link_url": "https://www.unifr.ch/regard/fr/", "canceled": "False", "cancel_reason": "", "place_and_room": "GC C2 413", "url_place_and_room": "https://plan.epfl.ch/?room=gcc2413", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<a href=\"http://www.bysika.com//\">Afi Sika Kuzeawu,certified systemic coach & psychologist</a>", "organizer": "<a href=\"https://www.unifr.ch/regard/en/\"><strong>REGARD</strong></a>", "contact": "<a href=\"mailto:[email protected]\">Chantal Mellier</a> ou <a href=\"mailto:[email protected]\">Kristin Becker</a>", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/114885/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/3/?format=api", "https://memento.epfl.ch/api/v1/mementos/4/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/21/?format=api", "https://memento.epfl.ch/api/v1/mementos/27/?format=api" ] }, { "id": 71070, "title": "Vision & Cognition // Lina Teichmann: From Light to Perception: Probing the temporal dynamics of colour vision", "slug": "vision-cognition-lina-teichmann-from-light-to-perc", "event_url": "https://memento.epfl.ch/event/vision-cognition-lina-teichmann-from-light-to-perc", "visual_url": "https://memento.epfl.ch/image/32448/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/32448/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/32448/max-size.jpg", "lang": "en", "start_date": "2026-04-22", "end_date": "2026-04-22", "start_time": "14:00:00", "end_time": "15:00:00", "description": "", "image_description": "", "creation_date": "2026-02-09T02:45:43", "last_modification_date": "2026-02-09T02:45:43", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 2510", "url_place_and_room": "https://plan.epfl.ch/?room==SV%202510", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Lina Teichmann, University of Geneva", "organizer": "SV BMI LPSY\r\n\r\nHost: Michael Herzog", "contact": "[email protected] ", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/119617/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/19/?format=api" ] }, { "id": 71300, "title": "BMI Seminar // Seung-Hee Lee: Balance between stability and flexibility", "slug": "bmi-seminar-seung-hee-lee-balance-between-stabilit", "event_url": "https://memento.epfl.ch/event/bmi-seminar-seung-hee-lee-balance-between-stabilit", "visual_url": "https://memento.epfl.ch/image/32657/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/32657/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/32657/max-size.jpg", "lang": "en", "start_date": "2026-05-22", "end_date": "2026-05-22", "start_time": "09:15:00", "end_time": "10:15:00", "description": "<p>TBD</p>", "image_description": "", "creation_date": "2026-03-04T18:39:30", "last_modification_date": "2026-03-04T18:44:47", "link_label": "Web Page", "link_url": "https://pure.kaist.ac.kr/en/persons/seung-hee-lee/publications/", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 2510", "url_place_and_room": "https://plan.epfl.ch/?room==SV%202510", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Seung-Hee Lee, Dept. of Biological Sciences, KAIST, South Korea", "organizer": "SV BMI LSENS\r\n\r\nHost: Carl Petersen", "contact": "[email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/119975/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/19/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api" ] }, { "id": 70040, "title": "“The end of KRAS cancers?”", "slug": "the-end-of-kras-cancers", "event_url": "https://memento.epfl.ch/event/the-end-of-kras-cancers", "visual_url": "https://memento.epfl.ch/image/31503/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/31503/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/31503/max-size.jpg", "lang": "en", "start_date": "2026-05-07", "end_date": "2026-05-07", "start_time": "12:15:00", "end_time": "13:15:00", "description": "<strong>A Lola and John Grace Distinguished Lecture in Cancer Research</strong>\r\n<div class=\"elementor-element elementor-element-98cefd8 elementor-widget elementor-widget-heading\">\r\n<div class=\"elementor-widget-container\"><br>\r\nFrank McCormick, PhD, is a Professor at the UCSF Helen Diller Family Comprehensive Cancer Center and holds the David A. Wood Chair of Tumor Biology and Cancer Research. Prior to joining the UCSF faculty, Dr. McCormick pursued cancer-related work with several Bay Area biotechnology firms and held positions with Cetus Corporation (Director of Molecular Biology, 1981-1990; Vice President of Research, 1990-1991) and Chiron Corporation, where he was Vice President of Research. In 1992 he founded Onyx Pharmaceuticals, a company dedicated to developing new cancer therapies, and served as its Chief Scientific Officer until 1996. At Onyx Pharmaceuticals, he initiated drug discovery efforts that led to the approval of Sorafenib in 2005 for treatment of renal cell cancer, and for liver cancer in 2007, and the approval of ONYX-015 in 2006 in China for treatment of nasopharyngeal cancer. In addition, Dr. McCormick’s group led to the identification of the CDK4 kinase inhibitor, Palbociclib, approved for treating advanced breast cancer. Dr. McCormick's current research interests center on ways of targeting Ras proteins and their regulators, including the NF1 protein neurofibromin.<br>\r\n<br>\r\nDr. McCormick was Director of the Helen Diller Family Comprehensive Cancer Center from 1997 to 2014 and he served as President, 2012-2013, for the American Association for Cancer Research. Since 2013, Dr. McCormick has led the National Cancer Institute’s Ras Initiative at the Frederick National Laboratories for Cancer Research overseeing the national effort to develop therapies against Ras-driven cancers. Dr. McCormick was recently awarded (September 2025) the Inaugural Stephenson Global Prize Award in recognition of his research and discoveries that have transformed the field of RAS-driven cancers. <br>\r\n<br>\r\nDr. McCormick is the author of over 430 scientific publications and holds more than 20 issued patents and is a Fellow of the Royal Society and a member of the National Academy of Sciences.<br>\r\n </div>\r\n</div>\r\n\r\n<div class=\"elementor-element elementor-element-e552a16 elementor-widget elementor-widget-text-editor\">\r\n<div class=\"elementor-widget-container\"> </div>\r\n</div>", "image_description": "", "creation_date": "2025-10-07T11:05:07", "last_modification_date": "2026-01-06T12:15:21", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/97039045251?pwd=WDFjUGV3Y1FxeG9rTUIrOGpiUXhLQT09", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<strong><em>Frank McCormick, PhD, FRS, DSc (Hon), </em></strong>UCSF Helen Diller Family Comprehensive Cancer Center and David A. Wood Chair of Tumor Biology and Cancer Research", "organizer": "Prof. Doug Hanahan", "contact": "Lisa Smith, ISREC Administrative Assistant", "is_internal": "True", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "Grace Lecture, cancer", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/118018/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/26/?format=api" ] }, { "id": 70058, "title": "BMI Distinguished Seminar // Mitra Hartmann: Touching the world and the wind: sensorimotor control and flow sensing with whiskers", "slug": "bmi-distinguished-seminar-mitra-hartmann-touching", "event_url": "https://memento.epfl.ch/event/bmi-distinguished-seminar-mitra-hartmann-touching", "visual_url": "https://memento.epfl.ch/image/31521/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/31521/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/31521/max-size.jpg", "lang": "en", "start_date": "2026-05-06", "end_date": "2026-05-06", "start_time": "12:15:00", "end_time": "13:15:00", "description": "<p>In rodents, the whisker (vibrissal) system supports behaviors ranging from locomotor guidance and object exploration to social interactions and anemotaxis (flow sensing). This versatility makes whisker-dependent behavior a powerful lens on sensorimotor control. The first part of the talk describes use of the whisker system to study embodied sensing and closed-loop sensorimotor control. On the sensory side, I will present models of whisker mechanics and signal encoding by primary sensory neurons. On the motor side, I will describe models of whisker musculature and emerging insights into the circuits that generate whisker movements. I will then outline key challenges in linking sensing to movement within an integrated closed-loop framework. The second part of the talk will highlight how whiskers interact with moving air. Bending and vibration encode direction and speed, including regimes where vibrations emerge at subcritical Reynolds numbers through coupled structural nonlinearities and fluid-structure interactions.<br>\r\n<br>\r\n<br>\r\n </p>", "image_description": "", "creation_date": "2025-10-08T12:14:17", "last_modification_date": "2026-03-02T13:22:44", "link_label": "Web Page", "link_url": "https://www.mccormick.northwestern.edu/research-faculty/directory/profiles/hartmann-mitra.html", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/64813563657", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Mitra Hartmann, Northwestern University, US", "organizer": "BMI Host: Pavan Ramdya", "contact": "[email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 1, "fr_label": "Tout public", "en_label": "General public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/118047/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/19/?format=api", "https://memento.epfl.ch/api/v1/mementos/88/?format=api" ] } ] }
