retrieve:
Return the details about the given Memento id.

list:
List all Memento objects.

GET /api/v1/mementos/9/events/?format=api&offset=30&ordering=fr_label
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

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            "id": 71819,
            "title": "Be Seen and Heard - Seminar and Workshop",
            "slug": "be-seen-and-heard-seminar-and-workshop",
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            "start_date": "2026-06-10",
            "end_date": "2026-06-10",
            "start_time": "12:00:00",
            "end_time": "17:15:00",
            "description": "<p>The BIOP and SV Communications teams invite you to a <strong>Seminar </strong>and an afternoon of <strong>hands-on</strong> sessions on best practices and tools for communicating your data.<br>\r\n<br>\r\n<u><strong>Program</strong></u><br>\r\n<br>\r\n<strong>12:00 - 13:15 - Seminar</strong>\r\n</p><ul>\r\n\t<li>Introductory talk - <em>Arne Seitz</em></li>\r\n\t<li>EPFL Standard guidelines - <em>Eva Schier &amp; Laurence Mauro</em></li>\r\n\t<li>How to create impactful and effective posters - <em>Eva Schier &amp; Laurence Mauro</em></li>\r\n</ul>\r\n<strong>13:30 - 17:15 - Workshop </strong>(limited to 30 participants)\r\n\r\n<ul>\r\n\t<li>Image Ethics &amp;  Quarep’s checklist - <em>Arne Seitz</em></li>\r\n\t<li>Make use of OMERO to augment your figure with interactive content - <em>Rémy Dornier</em></li>\r\n\t<li>How to create 3D rendered data, make videos and publish them on mediaspace - <em>Romain Guiet</em></li>\r\n\t<li>Make use of story telling to make your talk more engaging - <em>Anjalie Schlaeppi</em></li>\r\n</ul>\r\n<br>\r\nCome and learn to make the best of your data!<br>\r\n<br>\r\n<a href=\"https://forms.gle/6LkaftTrDQpFdchY9\">Free - registration mandatory</a> <em>You can register for the seminar only, the afternoon workshops only, or the full program.</em>",
            "image_description": "",
            "creation_date": "2026-05-06T15:36:11",
            "last_modification_date": "2026-05-12T17:06:56",
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            "place_and_room": "AI 1153",
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            "organizer": "BIOP &amp; SV Communications Teams",
            "contact": "[email protected]",
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            "id": 70697,
            "title": "SUPER SANDWICH SEMINAR",
            "slug": "super-sandwich-seminar-359",
            "event_url": "https://memento.epfl.ch/event/super-sandwich-seminar-359",
            "visual_url": "https://memento.epfl.ch/image/32117/200x112.jpg",
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            "lang": "en",
            "start_date": "2026-06-11",
            "end_date": "2026-06-11",
            "start_time": "12:00:00",
            "end_time": "13:00:00",
            "description": "<p>Triple S (Super Sandwich Seminar) will feature 3 speakers per week, each presenting for 15 minutes, followed by a 5 minutes Q&amp;A session.</p>",
            "image_description": "",
            "creation_date": "2025-12-16T15:54:32",
            "last_modification_date": "2025-12-16T15:56:14",
            "link_label": "",
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            "speaker": "Carmelo Covato -<em> Waszak Lab; </em>Chiara Paolantoni , <em>McCabe Lab</em>; Jillian Love, <em>Karthaus Lab</em>",
            "organizer": "Prof. Pierre Gönczy",
            "contact": "Lisa Smith, ISREC Administrative Assistant",
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            "keywords": "Super Sandwich, cancer",
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        {
            "id": 71801,
            "title": "Bioengineering Seminar - Professor Jing Yan - Single-cell Imaging of Microbial Communities across Different Spatial and Temporal Scales",
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            "start_date": "2026-06-12",
            "end_date": "2026-06-12",
            "start_time": "13:00:00",
            "end_time": "14:00:00",
            "description": "<p>Biofilm is an important lifestyle of bacteria where bacterial cells collectively form surface-associated aggregates embedded in a polymeric matrix they secrete. Important in industry and medicine, biofilms also represent a unique form of growing active matter with unique physical and material properties. In this talk, I will highlight our recent work on developing a platform for imaging live, growing biofilm at single-cell resolution, using <em>Vibrio cholerae </em>as the model organism. I will show how bacterial cells physically communicate with each other and the environment to form ordered architecture reminiscent of  liquid crystals. Moreover, I will talk about our recent discovery that heterogeneity in gene expression leads to unexpected pattern formation in biofilm through a drag-based sorting mechanism. I will also highlight ongoing research in the lab on extending the imaging capability to more natural environments including marine animal hosts. I will end by showing our recent findings on the mechanical properties of the extracellular matrix that underlie the architecture of the biofilm.</p>",
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            "creation_date": "2026-05-05T13:16:32",
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            "speaker": "Professor Jing Yan, Assistant Professor, Molecular, Cellular and Developmental Biology, Yale University",
            "organizer": "Professor Alexandre Persat",
            "contact": "[email protected]",
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        {
            "id": 71852,
            "title": "Engineered DCs reprogram the TME to unleash immunotherapy and CAR-T efficacy in lung cancer models",
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            "event_url": "https://memento.epfl.ch/event/engineered-dcs-reprogram-the-tme-to-unleash-immuno",
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            "start_date": "2026-06-12",
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            "start_time": "17:00:00",
            "end_time": null,
            "description": "<p>Thesis Director: Prof. M. De Palma,<br>\r\nMolecular Life Sciences doctoral program<br>\r\nThesis Nr. 11572<br>\r\n<br>\r\nTo take part in the public defense, please contact directly the speaker</p>",
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            "creation_date": "2026-05-12T14:59:02",
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            "speaker": "<strong>Luqing LI</strong>",
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        {
            "id": 71900,
            "title": "U.S. CDMRP – Breast Cancer Research Program | Research Funding",
            "slug": "us-cdmrp-breast-cancer-research-program-research-5",
            "event_url": "https://memento.epfl.ch/event/us-cdmrp-breast-cancer-research-program-research-5",
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            "start_date": "2026-06-12",
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            "description": "<strong>Aim</strong>: Through the Congressionally Directed Medical Research Program (CDMRP), the Department of Defense is announcing the 2026 <strong>Breast Cancer Research Program</strong> <strong>(BCRP)</strong> Awards. Several award programs are available:\r\n<ul>\r\n\t<li>The <strong>Breakthrough Awards</strong> supports promising research that has high potential to lead to or make breakthroughs in breast cancer. The Breakthrough Award is structured with four different funding levels. Each level has a defined research scope :\r\n\t<ul>\r\n\t\t<li><u>Funding Level 1</u>: Innovative, high-risk/high-reward research that is in the earliest stages of idea development or is an untested theory that addresses an important problem.</li>\r\n\t\t<li><u>Funding Level 2</u>: Research that is already supported by substantial preliminary or published data and strongly validates clinical translation in a well-defined context within the breast cancer landscape.</li>\r\n\t\t<li><u>Funding Level 3</u><strong>: </strong>Advanced translational studies with a high degree of project readiness.</li>\r\n\t\t<li><u>Funding Level 4</u><strong>: </strong>Large-scale projects that will transform and revolutionize the clinical management and/or prevention of breast cancer. Human clinical trials are required.</li>\r\n\t</ul>\r\n\t</li>\r\n\t<li>The <strong>Clinical Research Extension Award</strong> aims to extend the data collection, follow-up, and analysis of breast cancer clinical research studies. Proposed research may entail a deeper molecular analysis of clinical samples, initiation of new correlative studies, biomarker validation, or continuing clinical follow-up of patients currently/previously enrolled in an open/ongoing or completed clinical trial.</li>\r\n\t<li>The <strong>Era of Hope Scholar Award</strong> supports individuals early in their careers who have demonstrated significant potential to effect meaningful change in breast cancer. These individuals should be exceptionally talented scientists who have shown that they are the “best and brightest” in their field(s)</li>\r\n\t<li>The <strong>Transformative Breast Cancer Consortium Award</strong> is designed to support large-scale, multidisciplinary and multi-institutional consortia that address major challenges in breast cancer through tightly integrated and collaborative research efforts. It enables up to five Principal Investigators, including a Consortium Director, to work within a coordinated framework where all project components are aligned toward a shared central hypothesis. The award specifically aims to foster innovative and paradigm-shifting approaches that go beyond the capabilities of individual laboratories, requiring strong integration across scientific, administrative, and logistical aspects, as well as the active involvement of breast cancer advocates and cross-disciplinary expertise.</li>\r\n\t<li>The <strong>Transformative Breast Cancer Consortium Development Award</strong> is intended to provide successful applicants the time and resources needed to bring investigators and breast cancer advocates together to establish a consortium framework and conduct preliminary research to support application to a future, full Transformative Breast Cancer Consortium Award (pending availability of funds). This is a development award and is a separate mechanism from the full consortium award. Recipients of the FY26 Transformative Breast Cancer Consortium Development Award are expected to submit an application to compete for the full Transformative Breast Cancer Consortium Award anticipated to be offered in a future fiscal year(s).</li>\r\n</ul>\r\n<br>\r\nAll applications must align with at least one BCRP Overarching Challenge. The FY26 BCRP Challenges are listed at the end of this announcement.<br>\r\n<br>\r\n<strong>Funding</strong>:      <br>\r\nBreakthrough 1: $750K - $1.25M<br>\r\nBreakthrough 2: $1.65M - $3.35M<br>\r\nBreakthrough 3: $5.6M - $7M<br>\r\nBreakthrough 4: max. $21M<br>\r\nClinical Research Extension: $7M - $8.4M<br>\r\nEra of Hope: max. $4.9M<br>\r\nTransformative Breast Cancer Consortium Award: max. $35M<br>\r\nTransformative Breast Cancer Consortium Development Award: max. $140K<br>\r\n<sub>Note: Cost caps are <strong><em>total costs (direct plus indirect costs).</em> </strong>In accordance with EPFL guidelines, budgets should include a 20% overhead, and the total budget must remain within the grant’s maximum allowable funding.</sub><br>\r\n<br>\r\n<strong>Duration</strong>:     <br>\r\nBreakthrough 1: 3 years<br>\r\nBreakthrough 2: 3-4 years<br>\r\nBreakthrough 3: 4 years<br>\r\nBreakthrough 4: 4 years<br>\r\nClinical Research Extension: 4 years<br>\r\nEra of Hope: 4 years<br>\r\nTransformative Breast Cancer Consortium Award: 4 years<br>\r\nTransformative Breast Cancer Consortium Development Award: 1 year<br>\r\n<br>\r\n<strong>Eligibility: </strong>Applicants from international organizations or institutions are eligible to apply, and there are no citizenship restrictions. Programme-specific seniority levels are further defined <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=36241307&amp;fileType=pdf\">here</a>.<br>\r\n<br>\r\n<strong>How to Apply</strong>: Pre-applications are submitted through the <a href=\"https://ebrap.org/eBRAP/public/index.htm\">eBRAP platform</a>. They should contain contact information, a letter of intent, and a list of collaborators and key personnel as suggested on the platform. Full applications will be made via a Grants.gov workspace.<br>\r\n<br>\r\n<strong>Pre-Application Deadline:            </strong>\r\n\r\n<ul>\r\n\t<li><strong>12 June 2026, </strong>5:00 p.m. Eastern time\r\n\r\n\t<ul>\r\n\t\t<li>Breakthrough Award Level 3</li>\r\n\t\t<li>Breakthrough Award Level 4</li>\r\n\t\t<li>Transformative Breast Cancer Consortium Award</li>\r\n\t</ul>\r\n\t</li>\r\n\t<li><strong>24 June 2026, </strong>5:00 p.m. Eastern time\r\n\t<ul>\r\n\t\t<li>Breakthrough Award Level 1-2</li>\r\n\t\t<li>Transformative Breast Cancer Consortium Development Award</li>\r\n\t\t<li>Clinical Research Extension Award</li>\r\n\t\t<li>Era of Hope Scholar Award</li>\r\n\t</ul>\r\n\t</li>\r\n</ul>\r\n<br>\r\n<strong>Full Application Deadline</strong>:          \r\n\r\n<ul>\r\n\t<li><strong>08 July 2026, </strong>11:59 p.m. Eastern time\r\n\r\n\t<ul>\r\n\t\t<li>Breakthrough Award Level 1-2</li>\r\n\t\t<li>Transformative Breast Cancer Consortium Development Award</li>\r\n\t\t<li>Clinical Research Extension Award</li>\r\n\t\t<li>Era of Hope Scholar Award</li>\r\n\t</ul>\r\n\t</li>\r\n\t<li><strong>30 September 2026, </strong>11:59 p.m. Eastern time\r\n\t<ul>\r\n\t\t<li>Breakthrough Award Level 3</li>\r\n\t\t<li>Breakthrough Award Level 4</li>\r\n\t\t<li>Transformative Breast Cancer Consortium Award</li>\r\n\t</ul>\r\n\t</li>\r\n</ul>\r\n<br>\r\n<strong>Further information:</strong>\r\n\r\n<ul>\r\n\t<li>To find the full program announcements and to start your pre-application see <a href=\"https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=705101\">here</a></li>\r\n\t<li>A useful summary of each call can be found <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=36241307&amp;fileType=pdf\">here</a></li>\r\n\t<li>For questions about the eBRAP or Grants.gov platforms, contact the <a href=\"mailto:[email protected]\">Research Office</a>.</li>\r\n\t<li>Grants.gov Funding Opportunity Numbers:\r\n\t<ul>\r\n\t\t<li>Breakthrough 1: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=35855304&amp;fileType=doc&amp;otherMimeType=application/msword\">HT942526BCRPBTA12</a></li>\r\n\t\t<li>Breakthrough 2: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=35855304&amp;fileType=doc&amp;otherMimeType=application/msword\">HT942526BCRPBTA12</a></li>\r\n\t\t<li>Breakthrough 3: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=35855250&amp;fileType=doc&amp;otherMimeType=application/msword\">HT942526BCRPBTA3</a></li>\r\n\t\t<li>Breakthrough 4: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=35855218&amp;fileType=doc&amp;otherMimeType=application/msword\">HT942526BCRPBTA4</a></li>\r\n\t\t<li>Clinical Research Extension: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=35855261&amp;fileType=doc&amp;otherMimeType=application/msword\">HT942526BCRPCREA</a></li>\r\n\t\t<li>Era of Hope: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=35855289&amp;fileType=doc&amp;otherMimeType=application/msword\">HT942526BCRPEOHS</a></li>\r\n\t\t<li>Transformative Breast Cancer Consortium Award: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=35853313&amp;fileType=doc&amp;otherMimeType=application/msword\">HT942526BCRPTBCCA</a></li>\r\n\t\t<li>Transformative Breast Cancer Consortium Development Award: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=35855260&amp;fileType=doc&amp;otherMimeType=application/msword\">HT942526BCRPTBCCDA</a></li>\r\n\t</ul>\r\n\t</li>\r\n</ul>\r\n<br>\r\n<strong>FY26 BCRP Overarching Challenges</strong>\r\n\r\n<ul>\r\n\t<li>Prevent breast cancer (primary prevention)</li>\r\n\t<li>Identify determinants of breast cancer initiation, risk, or susceptibility</li>\r\n\t<li>Distinguish deadly from non-deadly breast cancers</li>\r\n\t<li>Conquer the problems of overdiagnosis and overtreatment</li>\r\n\t<li>Identify what drives breast cancer growth; determine how to stop it</li>\r\n\t<li>Identify why some breast cancers become metastatic</li>\r\n\t<li>Determine why/how breast cancer cells lie dormant for years and then re-emerge; determine how to prevent lethal recurrence</li>\r\n\t<li>Revolutionize treatment regimens by replacing them with ones that do all of the following: improve survival, are more effective, and are less toxic</li>\r\n\t<li>Eliminate the mortality associated with metastatic breast cancer</li>\r\n</ul>\r\nAlternatively, with adequate justification, applications may identify and address another overarching challenge related to <a href=\"https://cdmrp.health.mil/bcrp/pdfs/BreastCancerLandscape2025.pdf\">The Breast Cancer Landscape</a>. Justification must be provided in the application.<br>\r\n ",
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                "id": 3,
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                "en_label": "Free"
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            "category": {
                "id": 16,
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        {
            "id": 71586,
            "title": "Imaging Lunch: Introduction to image visualization with Napari",
            "slug": "imaging-lunch-introduction-to-image-visualizatio-2",
            "event_url": "https://memento.epfl.ch/event/imaging-lunch-introduction-to-image-visualizatio-2",
            "visual_url": "https://memento.epfl.ch/image/32920/200x112.jpg",
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            "start_date": "2026-06-17",
            "end_date": "2026-06-17",
            "start_time": "11:00:00",
            "end_time": "13:00:00",
            "description": "<div class=\"elementToProof\"><a href=\"https://docs.google.com/forms/d/e/1FAIpQLScPv1jP72ScE3HcMHFH_k8gQW23odk_Lk-v5K_3Hlnzj9sZ4g/viewform?usp=publish-editor\">Registration</a>\r\n<div class=\"elementToProof\">This workshop will introduce participants to the open-source Python-based viewer Napari designed for interactive visualization and analysis of large, multidimensional scientific data.</div>\r\n\r\n<div class=\"elementToProof\"> </div>\r\n\r\n<div class=\"elementToProof\">Napari enables real-time exploration and navigation of a wide range of n-dimensional, multimodal datasets (e.g 2D/3D images, time series, multichannel/hyperspectral data, as well as tracks, vectors, meshes, etc). Its plugin ecosystem and Python API make it highly extensible and well-suited for custom, reproducible analysis workflows.</div>\r\n\r\n<div class=\"elementToProof\"> </div>\r\n\r\n<div>Participants will learn how to use Napari to explore, annotate, and analyze data. The workshop begins with a brief introduction on basic concepts of 3D visualization, followed by an overview of the key features of the Napari viewer. We will then present how the viewer can be controlled programmatically as a Python object, then provide a short introduction to developing custom Napari plugins.</div>\r\n</div>",
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            "id": 70698,
            "title": "SUPER SANDWICH SEMINAR",
            "slug": "super-sandwich-seminar-361",
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            "lang": "en",
            "start_date": "2026-06-18",
            "end_date": "2026-06-18",
            "start_time": "12:00:00",
            "end_time": "13:00:00",
            "description": "<p>Triple S (Super Sandwich Seminar) will feature 3 speakers per week, each presenting for 15 minutes, followed by a 5 minutes Q&amp;A session.</p>",
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            "creation_date": "2025-12-16T15:56:43",
            "last_modification_date": "2025-12-16T15:58:24",
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            "speaker": "Yves Paychère -<em> Naef Lab; </em>Steffen Sonnentag, <em>Radtke Lab</em>; Kiruthika Kuma, <em>Antanasijevic Lab</em>",
            "organizer": "Prof. Pierre Gönczy",
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            "keywords": "Super Sandwich, cancer",
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            "id": 71846,
            "title": "Reprogramming Tumor-Infiltrating Exhausted CD8+ T Cells for Enhanced and Durable Antitumor Immunity",
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            "description": "<p>Thesis Director: Prof. L. Tang,<br>\r\nMolecular Life Sciences doctoral program<br>\r\nThesis Nr. 10996<br>\r\n<br>\r\nTo take part in the public defense, please contact directly the speaker</p>",
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            "place_and_room": "MED 0 1618",
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            "speaker": "<strong>Rongrong LI</strong>",
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            "keywords": "EDMS",
            "file": null,
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                "id": 12,
                "code": "SOUTE",
                "fr_label": "Soutenances de thèses",
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                "activated": true
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        {
            "id": 71922,
            "title": "U.S. CDMRP – Alzheimer's Research Program | Research Funding",
            "slug": "us-cdmrp-alzheimer-s-research-program-research-fun",
            "event_url": "https://memento.epfl.ch/event/us-cdmrp-alzheimer-s-research-program-research-fun",
            "visual_url": "https://memento.epfl.ch/image/33239/200x112.jpg",
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            "start_date": "2026-06-22",
            "end_date": "2026-06-22",
            "start_time": null,
            "end_time": null,
            "description": "<strong>Aim</strong>: Through the Congressionally Directed Medical Research Program (CDMRP), the Department of Defense is announcing the 2026 <strong>Alzheimer's Research Program (AZRP) </strong>Awards. Several award programs are available:\r\n<ul>\r\n\t<li>The <strong>Transforming Care Award </strong>aims to support well-designed, non-incremental clinical research that develops and implements interventions, innovations, and solutions to address critical challenges in dementia care. Projects should lead to improved quality of life, reduced caregiver burden and stress, and enhanced care delivery and outcomes for individuals living with AD/ADRD.</li>\r\n\t<li>The <strong>Transforming Diagnosis Award </strong>supports non-incremental, solution-oriented research that addresses critical barriers to timely and accurate diagnosis, disease monitoring, and prognosis in AD/ADRD. Projects should demonstrate clear potential to improve accessibility, clinical implementation, and the reliability of diagnostic and prognostic approaches.</li>\r\n\t<li>The <strong>Transforming Research Award </strong>supports non-incremental, high-impact research that aims to drive transformative advances in reducing risk and preventing the development of AD/ADRD. Projects should demonstrate strong potential to accelerate prevention strategies and deliver meaningful improvements in patient outcomes and quality of life.<strong> </strong>All projects must respond to one of the focus areas listed <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=36241238&amp;fileType=pdf\">here</a>.</li>\r\n</ul>\r\n<strong>Funding</strong>:\r\n\r\n<ul>\r\n\t<li>Transforming Care Award: $1.6M - $1.9M</li>\r\n\t<li>Transforming Diagnosis Award: $1.5M - $1.7M</li>\r\n\t<li>Transforming Research Award: max. $1M</li>\r\n</ul>\r\n<br>\r\n<sub>Note: Cost caps are <strong>total costs (direct plus indirect costs). </strong>In accordance with EPFL guidelines, budgets should include a 20% overhead, and the total budget must remain within the grant’s maximum allowable funding</sub><br>\r\n<br>\r\n<br>\r\n<strong>Duration</strong>:   \r\n\r\n<ul>\r\n\t<li>Transforming Care Award: 4 years</li>\r\n\t<li>Transforming Diagnosis Award: 4 years</li>\r\n\t<li>Transforming Research Award: 3 years</li>\r\n</ul>\r\n<strong>Eligibility: </strong>Applicants from international organizations or institutions are eligible to apply, and there are no citizenship restrictions. Program-specific seniority levels and eligibility criteria are further defined within each award mechanism <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=36243245&amp;fileType=pdf\">here</a>.<br>\r\n<br>\r\n<strong>How to Apply</strong>: Pre-applications are submitted through the <a href=\"https://ebrap.org/eBRAP/public/index.htm\">eBRAP platform</a>. They should contain contact information, a letter of intent, and a list of collaborators and key personnel as suggested on the platform. Full applications will be made via a Grants.gov workspace.<br>\r\n<br>\r\n<strong>Pre-Application Deadline: 22 June 2026, </strong>5:00 p.m. Eastern time<br>\r\n<strong>Full Application Deadline</strong>: <strong>24 September 2026</strong>, 11:59 p.m Eastern Time<br>\r\n<br>\r\n<strong>Further information:</strong>\r\n\r\n<ul>\r\n\t<li>To find the full program announcements and to start your pre-application see <a href=\"https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=719106\">here</a></li>\r\n\t<li>A useful summary of each call can be found <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=36243245&amp;fileType=pdf\">here</a></li>\r\n\t<li>For questions about the eBRAP or Grants.gov platforms, contact the <a href=\"mailto:[email protected]\">Research Office</a></li>\r\n\t<li>Grants.gov Funding Opportunity Numbers:\r\n\t<ul>\r\n\t\t<li>Transforming Care Award: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=36241229&amp;fileType=pdf\">HT942526AZRPTRCA</a></li>\r\n\t\t<li>Transforming Diagnosis Award: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=36241231&amp;fileType=pdf\">HT942526AZRPTRDA</a></li>\r\n\t\t<li>Transforming Research Award: <a href=\"https://ebrap.org/eBRAP/public/ViewFile.htm?fileId=36241238&amp;fileType=pdf\">HT942526AZRPTRRA</a></li>\r\n\t</ul>\r\n\t</li>\r\n</ul>",
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        {
            "id": 70928,
            "title": "BMI Distinguished Seminar // Yvette Fisher: Flexibility of visual input to the Drosophila head direction network",
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            "event_url": "https://memento.epfl.ch/event/bmi-distinguished-seminar-yvette-fisher-flexibilit",
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            "description": "<p>Many plasticity rules rely on adjusting the strength of synapses between pairs of cells based on their coincident activity. We uncovered a new mechanism for coincidence detection in the Drosophila head direction network. To maintain an accurate sense of direction, head direction neurons that signal orientation during navigation must learn to anchor to relevant external sensory cues in novel environments. Yet the synaptic mechanism for this form of unsupervised learning is unknown in any organism. In Drosophila, GABAergic visual inputs converge onto head direction neurons, and these inhibitory synapses change strength with experience to learn the relationship between visual landmarks and head direction. However, how coincident pre- and postsynaptic activity is detected across this inhibitory synapse is not understood. We discovered that neurons which release the monoamine octopamine close a feedback loop that conveys postsynaptic head direction activity onto presynaptic terminals of visual inputs. This octopamine pathway is required for anchoring the head direction network to visual cues. Furthermore, pairing structured activation of octopamine neurons with a visual cue is sufficient to drive rapid plasticity, even without postsynaptic head direction cell activity. Previous work has extensively characterized coincidence detection mechanisms at excitatory synapses; our work defines a novel mechanism for coincidence detection at an inhibitory synapse, in which postsynaptic activity is relayed via a neuromodulatory neuron onto presynaptic terminals.<br>\r\n </p>",
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            "speaker": "Yvette Fisher, UC Berkeley",
            "organizer": "SV BMI Host: Pavan Ramdya",
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