A role for regulated cell polarity in defining growth vectors in the developing skeleton

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Event details

Date 05.06.2009
Hour 12:15
Speaker Prof. Andrew Dudley, PhD Northwestern University/BMBCB Evanston, IL (USA)
Location
Salle SV 1717a
Category Conferences - Seminars
Abstract : One remarkable feature of growing long bones is the arrangement of flattened chondrocytes in columns arrayed parallel to the axis of growth. These chondrocyte columns elongate via convergent extension by cell intercalation, a process regulated by noncanonical Wnt/frizzled signaling. We propose that regional differences in chondrocyte stacking provides one mechanism that generates the unique morphologies of individual bones.

Practical information

  • General public
  • Free

Contact

  • Prof. Daniel Constam

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