A role for regulated cell polarity in defining growth vectors in the developing skeleton

Event details
Date | 05.06.2009 |
Hour | 12:15 |
Speaker | Prof. Andrew Dudley, PhD Northwestern University/BMBCB Evanston, IL (USA) |
Location |
Salle SV 1717a
|
Category | Conferences - Seminars |
Abstract : One remarkable feature of growing long bones is the arrangement of flattened chondrocytes in columns arrayed parallel to the axis of growth. These chondrocyte columns elongate via convergent extension by cell intercalation, a process regulated by noncanonical Wnt/frizzled signaling. We propose that regional differences in chondrocyte stacking provides one mechanism that generates the unique morphologies of individual bones.
Practical information
- General public
- Free
Contact
- Prof. Daniel Constam